PMID: 75438Feb 25, 1978Paper

A double-blind controlled crossover trial of an antigen-avoidance diet in atopic eczema

Lancet
D J AthertonC E Chilvers

Abstract

20 out of 36 children (aged two to eight years) with atopic eczema completed a twelve-week, double-blind, controlled, crossover trial of an egg and cows' milk exclusion diet. During the first and third four-week periods, patients on an egg and cows' milk exclusion diet received a soya-based milk substitute (trial period) or an egg and cows' milk preparation (control period). Response was assessed in terms of eczema activity, number of areas affected, pruritus, sleeplessness, and antihistamine usage while on the two diets. During the middle period patients resumed their normal diet to minimise any carry-over effect. 14 patients responded more favourably to the antigen-avoidance diet than to the control diet, whereas only 1 responded more favourably to the control diet than the trial diet. Patients experienced more benefit during the first diet period than the second, whatever the nature of the diet. There was no correlation between a positive prick test to egg and cows' milk antigen and response to the trial diet.

References

Feb 12, 1977·Lancet·D J MatthewM W Turner

❮ Previous
Next ❯

Citations

Jan 1, 1981·Springer Seminars in Immunopathology·D Y Leung, R S Geha
Jun 1, 1980·Agents and Actions·N E Byars, R W Ferraresi
Jan 1, 1984·Indian Journal of Pediatrics·H PariharV Kumar
Feb 1, 1984·The Journal of Allergy and Clinical Immunology·J M Hanifin
Apr 1, 1996·The Journal of Allergy and Clinical Immunology·H Majamaa, E Isolauri
Aug 6, 1983·Lancet·S J BentleyK J Rix
May 28, 1994·Lancet·B PrzybillaF Ruëff
Jun 5, 2003·Clinics in Dermatology·Hugh A Sampson
Jun 29, 2001·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·C CaffarelliG de Angelis
Apr 12, 2001·Allergy·T Werfel
Apr 4, 2001·Alimentary Pharmacology & Therapeutics·S ZarM J Benson
Oct 17, 1991·The New England Journal of Medicine
Jan 1, 1988·Nutrition Research Reviews·A Ferguson, K C Watret
Dec 1, 1979·The Proceedings of the Nutrition Society·A M Denman
Jun 1, 1983·The Proceedings of the Nutrition Society·R S Barnetson, T G Merrett
Oct 1, 1988·Pediatric Clinics of North America·J B Broadbent, H A Sampson
Jun 1, 1982·The British Journal of Dermatology·D J AthertonJ Elvidge
Feb 1, 1992·The British Journal of Dermatology·M P Sheehan, D J Atherton
Oct 1, 1996·The British Journal of Dermatology·A Y Finlay
Nov 1, 1991·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·D J Atherton
Dec 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M H Lessof
Jan 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C CaffarelliD J Atherton
Jul 1, 1995·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A M Edwards
Apr 30, 1998·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·R LeverT Aitchison
Aug 1, 1984·Australian Paediatric Journal·A Kemp
Nov 14, 1997·Acta Paediatrica·D de BoissieuC Dupont
Jul 26, 2005·Archives of Disease in Childhood·S T Holgate, G Lack
Nov 1, 1982·Archives of Disease in Childhood·L S Taitz
Sep 1, 1982·Archives of Disease in Childhood·R P Ford, B Taylor
Mar 1, 1983·Archives of Disease in Childhood·R PaganelliR J Levinsky
Aug 1, 1986·Archives of Disease in Childhood·A Cant
Apr 1, 1988·Archives of Disease in Childhood·F G MiskellyT G Merrett
Dec 1, 1989·Archives of Disease in Childhood·M G PikeD J Atherton
Jan 1, 1991·Archives of Disease in Childhood·J DevlinR H Stanton
Sep 1, 1995·Archives of Disease in Childhood·D C MabinT J David
Jun 5, 1998·Archives of Disease in Childhood·C CaffarelliD J Atherton
Feb 9, 1980·British Medical Journal·J F Soothill
Jun 13, 1981·British Medical Journal·R S Jones
Jun 20, 1981·British Medical Journal·A L Parke, G R Hughes
Oct 24, 1981·British Medical Journal·R S BarnetsonT G Merrett
Jan 9, 1982·British Medical Journal·J HarperN A Byrom
Sep 17, 1983·British Medical Journal·D J Atherton

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.