PMID: 6966882Jan 1, 1980Paper

A double-blind, cross-over study of the effects of terodiline in women with unstable bladder

Acta Pharmacologica Et Toxicologica
G EkmanU Ulmsten

Abstract

In a double-blind, cross-over study, the effects of terodiline were evaluated in 12 women with motor urge incontinence. The patients were investigated by simultaneous urethro-cystometry before and after treatment fo 2-week periods with placebo and terodiline 12.5 mg twice daily. The effects on subjective symptoms were also assessed. In all patients but one, terodiline increased the bladder capacity and also the bladder volume at which urgency was experienced. No effects on the urethral pressure profile or residual urine were found. Subjective improvement was reported by all but one of the patients. Placebo treatment had no effect on the measured parameters or on the subjective symptoms. No side effects were reported during any of the treatment periods. --It is concluded that terodiline can be used for treatment of female motor urge incontinence, and that it is a promising alternative to drugs presently used for this disorder.

References

Jan 1, 1977·Annual Review of Pharmacology and Toxicology·A Fleckenstein
Jan 1, 1979·Urologia Internationalis·T RudU Ulmsten
Jan 1, 1977·Scandinavian Journal of Urology and Nephrology·U Ulmsten, K E Andersson
Aug 1, 1978·Acta Pharmacologica Et Toxicologica·A FormanU Ulmsten
Jan 1, 1976·Scandinavian Journal of Urology and Nephrology·M Asmussen, U Ulmsten
Jan 1, 1976·Acta Obstetricia Et Gynecologica Scandinavica·M Asmussen, U Ulmsten
Dec 17, 1976·Deutsche medizinische Wochenschrift·J BödekerR Nagel
Oct 1, 1970·The Journal of Physiology·N Ambache, M A Zar

❮ Previous
Next ❯

Citations

Apr 1, 1989·British Journal of Urology·A L HellströmU Jodal
May 1, 1988·Scandinavian Journal of Primary Health Care·M ElmérT Adolfsson
Nov 1, 1987·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·B LindekeB Vangbo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.