PMID: 17557Jan 1, 1976Paper

A double-blind trial of penbutolol: a new beta-receptor blocking agent in the treatment of angina pectoris

The Journal of International Medical Research
A K AgarwalM Hasan


A double-blind placebo controlled study of angina pectoris with penbutolol was undertaken in parallel groups in fifty-two patients. The duration of the study was six weeks. The dosage range for penbutolol was 8 mg to 50 mg per day. Six patients were dropped from the analysis. Seventeen patients (81%) in the penbutolol series exhibited a 50% reduction in anginal attacks, NTG consumption and subjective improvement. Significant reduction in nitrite intake was observed. Effort tolerance was improved significantly in those receiving penbutolol. Penbutolol was well-tolerated.


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Nov 1, 1983·British Journal of Clinical Pharmacology·B SilkeS H Taylor
Jan 1, 1986·The Journal of International Medical Research·S S SangheraD G Parsons
Jan 1, 1985·The Journal of International Medical Research·L C SlegersC A Sumajow

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