A driving simulation task: correlations with Multiple Sleep Latency Test

Brain Research Bulletin
Fabio PizzaFabio Cirignotta

Abstract

Sleepiness and driving is a dangerous combination that causes thousands of crashes each year resulting in injury and death. In the last few years, driving simulators have been used to study the performance decrements associated with drowsiness. We correlated performances of a driving simulation task in healthy volunteers in different alertness conditions with objective (MSLT: Multiple Sleep Latency Test) and subjective (SSS: Stanford Sleepiness Scale; VAS: Visual Analogue Scale) sleepiness measurements. The subjects were tested on two days, after a normal night of sleep and after a night of complete sleep deprivation. The study consists of four sessions of MSLT, each one followed by subjective measurements of sleepiness and by a 30 min driving simulation task with a monotonous driving scenario. The parameters that correlate most highly with MSLT are the standard deviation of lane position, the mean RT, crash frequency and exceeding the speed limit frequency. The monotonous driving simulation we adopted showed strong correlations with MSLT and subjective sleepiness scales in healthy subjects and is suitable to evaluate excessive daytime sleepiness in patients.

References

Jul 1, 1996·American Journal of Respiratory and Critical Care Medicine·C F GeorgeA Smiley
Jul 1, 1997·Accident; Analysis and Prevention·M G LennéJ R Redman
Apr 10, 1999·Accident; Analysis and Prevention·W B Verwey, D M Zaidel
Jul 26, 2002·International Journal of Clinical Pharmacology and Therapeutics·A IudiceL Murri

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Citations

Jul 4, 2012·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Ebrahim RazmpaBabak Saedi
Sep 30, 2014·Journal of Clinical and Experimental Neuropsychology·Sara MondiniGonia Jarema
Sep 1, 2017·PloS One·Shamsi Shekari SoleimanlooSimon S Smith
May 11, 2020·Sleep Medicine Clinics·Brian James Murray
Aug 31, 2021·Sleep Medicine Reviews·Anna W T CaiClare Anderson

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