A dual-route perspective on poor reading in a regular orthography: an fMRI study.

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Heinz WimmerGunther Ladurner

Abstract

This study examined functional brain abnormalities in dyslexic German readers who - due to the regularity of German in the reading direction - do not exhibit the reading accuracy problem of English dyslexic readers, but suffer primarily from a reading speed problem. The in-scanner task required phonological lexical decisions (i.e., Does xxx sound like an existing word?) and presented familiar and unfamiliar letter strings of existing phonological words (e.g., Taxi-Taksi) together with nonwords (e.g., Tazi). Dyslexic readers exhibited the same response latency pattern (words<pseudohomophones<nonwords) as nonimpaired readers, but latencies to all item types were much prolonged. The imaging results were suggestive for a different neural organization of reading processes in dyslexic readers. Specifically, dyslexic readers, in response to lexical route processes, exhibited underactivation in a left ventral occipitotemporal (OT) region which presumably is engaged by visual-orthographic whole word recognition. This region was also insensitive to the increased visual-orthographic processing demands of the sublexical route. Reduced engagement in response to sublexical route processes was also found in a left inferior parietal region, pr...Continue Reading

References

Jan 1, 1995·International Journal of Technology Assessment in Health Care·M Milner
Apr 6, 2000·Journal of Child Psychology and Psychiatry, and Allied Disciplines·A GallagherM J Snowling
Sep 12, 2000·Mental Retardation and Developmental Disabilities Research Reviews·K R PughB A Shaywitz
Nov 30, 2000·Proceedings of the National Academy of Sciences of the United States of America·E TempleJ D Gabrieli
Jun 14, 2001·Thorax·A Woodcock
Mar 20, 2002·Neuropsychologia·Heinz Mayringer, Heinz Wimmer
Mar 22, 2002·NeuroImage·Christopher R GenoveseThomas Nichols
Apr 19, 2002·Brain : a Journal of Neurology·Laurent CohenStanislas Dehaene
Apr 26, 2002·Neuroreport·Martin KronbichlerHeinz Wimmer
May 29, 2002·NeuroImage·K J FristonJ Ashburner
Jul 26, 2003·NeuroImage·Cathy J Price, Joseph T Devlin
Sep 4, 2003·Mental Retardation and Developmental Disabilities Research Reviews·Bruce D McCandliss, Kimberly G Noble
Oct 16, 2003·Journal of Experimental Child Psychology·Johannes C ZieglerGerd Schulte-Körne
Jun 19, 2004·Journal of Neural Transmission·C GrünlingB Blanz
Sep 8, 2004·Neuropsychologia·Laurent CohenSophie Ferrieux
Sep 30, 2004·Journal of Cognitive Neuroscience·James R BoothM Marsel Mesulam
Oct 28, 2004·Journal of Learning Disabilities·J E Jiménez González, I Hernández Valle
Oct 30, 2004·Journal of Learning Disabilities·C D Porpodas
Mar 9, 2005·Developmental Neuropsychology·Donatella SpinelliPierluigi Zoccolotti
May 3, 2005·Brain and Language·Pierluigi ZoccolottiDonatella Spinelli
Jun 14, 2005·Trends in Cognitive Sciences·Stanislas DehaeneFabien Vinckier
Jan 6, 2006·Neurocase·Kristina MollHeinz Wimmer
Apr 20, 2006·Neuropsychologia·Martin KronbichlerHeinz Wimmer
Jul 15, 2006·Journal of Cognitive Neuroscience·Joseph T DevlinPaul M Matthews
Aug 29, 2006·Brain Research·Simona Maria BrambatiDaniela Perani
Nov 1, 2006·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Fan CaoJames R Booth
Mar 16, 2007·Proceedings of the National Academy of Sciences of the United States of America·Fumiko HoeftJohn D E Gabrieli
Apr 21, 2007·Annals of Neurology·Bennett A ShaywitzSally E Shaywitz
Aug 19, 2007·Annals of Neurology·Lisa E PhiliposeArgye E Hillis
Oct 13, 2007·Journal of Cognitive Neuroscience·Martin KronbichlerHeinz Wimmer
Jan 9, 2008·NeuroImage·Jennifer Lynn BrunoJason G Goldman
May 15, 2008·Journal of Cognitive Neuroscience·Martin KronbichlerHeinz Wimmer
Mar 17, 2010·Cognition·Stefan HawelkaHeinz Wimmer
Aug 6, 2010·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Tarik HadzibeganovicMax Coltheart

❮ Previous
Next ❯

Citations

Jan 5, 2012·Annals of Dyslexia·Paz Suárez-Coalla, Fernando Cuetos
Mar 23, 2011·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Despina PaiziPierluigi Zoccolotti
Jun 19, 2013·Brain Structure & Function·Katarzyna JednorógAnna Grabowska
Oct 17, 2015·Perceptual and Motor Skills·David S MatherLona M Mcrae
Apr 3, 2012·Brain and Cognition·Susana AraújoAlexandra Reis
Sep 21, 2011·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Robert D McIntosh, Joanna L Brooks
Apr 6, 2011·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jennifer A Foley, Sergio Della Sala
Oct 20, 2010·Dyslexia : the Journal of the British Dyslexia Association·Heinz Wimmer, Matthias Schurz
Aug 30, 2014·Cerebral Cortex·Matthias SchurzMartin Kronbichler
Jun 5, 2015·Frontiers in Psychology·Joan Guàrdia-OlmosEsteve Gudayol-Ferré
Feb 23, 2011·NeuroImage·Fabio RichlanHeinz Wimmer
May 10, 2011·Trends in Cognitive Sciences·Cathy J Price, Joseph T Devlin
Jan 1, 2013·NeuroImage. Clinical·Muna van Ermingen-MarbachStefan Heim
Dec 22, 2014·Brain and Language·Susana AraújoKarl Magnus Petersson
Jan 11, 2012·Brain and Language·Stefan HeimKatrin Amunts
May 9, 2012·Neuropsychologia·Yulia Oganian, Merav Ahissar
Sep 29, 2012·Neuropsychologia·Mohamed L SeghierCathy J Price
Jul 28, 2009·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Maria De LucaPierluigi Zoccolotti
Aug 6, 2010·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Tarik HadzibeganovicMax Coltheart
Jul 30, 2014·Frontiers in Human Neuroscience·Muriel A LobierSylviane Valdois
Jun 7, 2014·Frontiers in Human Neuroscience·Fabio Richlan
Jul 30, 2014·Frontiers in Human Neuroscience·Gorka Fraga GonzálezMaurits W van der Molen
Nov 9, 2016·Neuroscience and Biobehavioral Reviews·Roeland HancockFumiko Hoeft
Apr 26, 2017·Translational Psychiatry·M O UlfarssonK Stefansson
Sep 18, 2013·Clinical EEG and Neuroscience·Andrés Antonio González-GarridoElizabeth Rodríguez-Santillán
Dec 5, 2017·The Spanish Journal of Psychology·Joan Guardia-OlmosAndrés González-Garrido
Mar 3, 2018·Current Developmental Disorders Reports·Lisa Kronbichler, Martin Kronbichler
Oct 10, 2019·Human Brain Mapping·Sikoya M AshburnGuinevere F Eden
Mar 29, 2019·Brain Imaging and Behavior·Amy E MargolisRachel Marsh

❮ Previous
Next ❯

Methods Mentioned

BETA
SMA

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.