Nov 14, 2018

A factorial cluster-randomised controlled trial combining home-environmental and early child development interventions to improve child health and development: rationale, trial design and baseline findings.

BioRxiv : the Preprint Server for Biology
Stella M HartingerDaniel Mäusezahl

Abstract

Background: Exposure to unhealthy environments and poor cognitive development are the main risk factors that affect children's health and wellbeing in low- and middle-income countries. Interventions that simultaneously address several risk factors at the household level have great potential to reduce these negative effects. We present the design and baseline findings of a cluster-randomised controlled trial to evaluate the impact of an integrated home-environmental intervention package and an early child development programme to improve diarrhoea, acute respiratory infections and childhood developmental outcomes in children under 36 months of age living in resource-limited rural Andean Peru. Methods: We collected baseline data on children's developmental performance, health status and demography as well as microbial contamination in drinking water. In a sub-sample of households, we measured indoor and personal 24-hour air concentration levels of carbon monoxide (CO) and fine particulate matter (PM2.5). Results: We recruited and randomised 317 children from 40 community-clusters to four study arms. At baseline, all arms had similar health and demographic characteristics, and the developmental status of children was comparable be...Continue Reading

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Mentioned in this Paper

Study
Acute Respiratory Infections
Environment
Coliform bacteria
Home Environment
Iron Deficiency
Carbon Monoxide
Cognitive Development
Clinical Trials
Analysis

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