A fast B1-mapping method for the correction and normalization of magnetization transfer ratio maps at 3 T

NeuroImage
Steffen VolzRalf Deichmann

Abstract

In neuroimaging, there is increasing interest in magnetization transfer (MT) techniques which yield information about bound water protons. One of the main applications is the investigation of the myelin integrity in the central nervous system (CNS). However, several problems may arise, in particular at high magnetic field strengths: B1 inhomogeneities may yield deviations of the MT saturation angle and thus non-uniformities of the measured MT ratio (MTR). This effect can be corrected for but requires in general additional time consuming B1 mapping. Furthermore, increased values of the specific absorption rate (SAR) may require a reduction of the saturation angle for individual subjects, impairing comparability of results. In this work, a B1 mapping method based on magnetization-prepared FLASH with slice selective preparation and excitation pulses and correction for relaxation effects is presented, yielding B1 maps with whole brain coverage, an in-plane resolution of 4 mm, a slice thickness of 3 mm, and a clinically acceptable duration of 46 s. The method is tested both in vitro and in vivo and applied in a subsequent in vivo study to show that MTR values in human brain tissue depend approximately linearly on the preparation ang...Continue Reading

References

Sep 1, 1990·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·D G NorrisD Leibfritz
Jan 1, 1990·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·A Haase
Jan 1, 1990·Magnetic Resonance Imaging·C H OhI K Mun
Feb 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·A EricssonG O Sperber
Jan 1, 1993·Magnetic Resonance Imaging·S AkokaA Le Pape
Nov 5, 1997·NeuroImage·J Ashburner, K Friston
Apr 9, 1999·Journal of Magnetic Resonance Imaging : JMRI·I BerryP S Tofts
May 8, 1999·Journal of Magnetic Resonance Imaging : JMRI·J P WansapuraW S Ball
Jul 6, 2000·NeuroImage·R DeichmannR Turner
Jul 10, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J T VaughanK Ugurbil
Feb 3, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J G SledG B Pike
Sep 7, 2004·Annals of Neurology·Klaus SchmiererDavid H Miller
Sep 12, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Seth A SmithPeter C M van Zijl
Nov 8, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·F Jiru, U Klose
Dec 28, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Vasily L Yarnykh
Aug 22, 2007·Radiology·Basil H RidhaPaul S Tofts
Aug 30, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Gunther HelmsPeter Dechent
Sep 26, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Glen R Morrell
Nov 26, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Gunther HelmsPeter Dechent
Dec 20, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kay Nehrke
Dec 20, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·C Preibisch, R Deichmann

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Citations

Dec 6, 2014·Radiological Physics and Technology·Shigeyoshi SaitoKenya Murase
Mar 8, 2016·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Amgad DrobyRalf Deichmann
Mar 25, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Gunther HelmsPeter Dechent
Dec 7, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Steffen VolzRalf Deichmann
Dec 23, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Vasily L Yarnykh
Jan 19, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kay Nehrke, Peter Börnert
Jun 14, 2014·Journal of Magnetic Resonance Imaging : JMRI·Alois M SprinkartPeter Börnert
Apr 16, 2014·NMR in Biomedicine·Wyger M BrinkAndrew G Webb
Apr 5, 2013·Journal of Magnetic Resonance Imaging : JMRI·Alina JurcoaneElke Hattingen
Feb 16, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kay NehrkePeter Börnert
Aug 1, 2015·Clinical Neuroradiology·E HattingenH H Schild
May 12, 2015·NMR in Biomedicine·Ulrike NöthRalf Deichmann
Mar 20, 2015·NMR in Biomedicine·Johannes WindschuhPeter Bachert
Nov 29, 2014·Journal of Magnetic Resonance Imaging : JMRI·Angèle LecocqJean-Philippe Ranjeva
Jan 20, 2015·Magnetic Resonance Imaging·Muge KaramanDaniel B Rowe
May 28, 2013·Journal of Magnetic Resonance·S VashaeeB J Balcom
May 7, 2016·Journal of Magnetic Resonance Imaging : JMRI·René-Maxime GracienJohannes C Klein
Feb 28, 2017·Journal of Magnetic Resonance Imaging : JMRI·René-Maxime GracienJohannes C Klein
Mar 5, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Mustapha Bouhrara, Richard G Spencer
Oct 24, 2018·Journal of Magnetic Resonance Imaging : JMRI·Benoit CombèsUNKNOWN EMISEP study group
Oct 9, 2019·The European Journal of Neuroscience·Christopher D RowleySilke Matura
Aug 28, 2020·Aging·Alexander SeilerRené-Maxime Gracien
Sep 5, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Manoj ShresthaRalf Deichmann
Sep 12, 2019·Frontiers in Neurology·René-Maxime GracienSimon Baudrexel
Oct 21, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Simon BaudrexelRalf Deichmann
Jul 3, 2020·Frontiers in Neuroscience·Michelle MaiwormRené-Maxime Gracien
Dec 23, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Roya AfshariOliver Bieri
Jul 1, 2018·Magnetic Resonance Imaging·Abinand C RejimonMustapha Bouhrara
May 7, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Christopher D RowleyChristine L Tardif

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