A Fatty Acid Mouth Rinse Decreases Self-Reported Hunger and Increases Self-Reported Fullness in Healthy Australian Adults: A Randomized Cross-Over Trial

Nutrients
Andrew CostanzoRussell Keast

Abstract

Fatty acid (FA) chemoreception in the oral cavity, known as fat taste, may trigger a satiety response that is homologous to FA chemoreception in the gastrointestinal tract. In addition, individuals with an impaired fat taste sensitivity are more likely to have an impaired satiety response. This study aimed to assess the effect of an FA mouth rinse on self-reported appetite, and to determine if the effect is modified by fat taste sensitivity. Thirty-one participants (age, 32.0 ± 8.4 y; body mass index (BMI), 26.1 ± 8.1 kg/m2) were studied on four separate days to evaluate the effect of a 20 mM oleic acid (OA) mouth rinse (in duplicate) compared to a control (in duplicate) on self-reported appetite by using a visual analogue scale (VAS) every 30 min for three hours following a standardized low-fat breakfast. The area under the curve ratings for fullness were greater (p = 0.003), and those for hunger were lower (p = 0.002) following the OA rinse compared to the control. The effect of the OA rinse was greater in individuals who were hypersensitive to fat taste compared to moderately sensitive and hyposensitive individuals for fullness (p < 0.010) and hunger (p < 0.010) ratings. In summary, an OA mouth rinse decreases self-reported ...Continue Reading

References

Sep 1, 1989·Journal of Gastroenterology and Hepatology·R HeddleL A Houghton
May 1, 1997·Digestive Diseases and Sciences·M WøjdemannJ F Rehfeld
Mar 7, 2000·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·A FlintA Astrup
Dec 22, 2000·The American Journal of Clinical Nutrition·M D RobertsonK N Frayn
Nov 21, 2001·Physiology & Behavior·R D Mattes
Apr 10, 2003·American Journal of Physiology. Gastrointestinal and Liver Physiology·Christine FeinleMichael Horowitz
Jun 27, 2009·American Journal of Physiology. Gastrointestinal and Liver Physiology·Ixchel M BrennanChristine Feinle-Bisset
Mar 4, 2010·The British Journal of Nutrition·Jessica E StewartRussell S J Keast
Feb 12, 2011·The American Journal of Clinical Nutrition·Jessica E StewartChristine Feinle-Bisset
Aug 11, 2011·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J E Stewart, R S J Keast
Jan 3, 2012·Journal of Lipid Research·Marta Yanina PepinoNada A Abumrad
Feb 19, 2014·Physiology & Behavior·Nina R Martínez-RuizOfelia Angulo
Mar 5, 2014·Chemical Senses·Robin M TuckerRichard D Mattes
Jun 26, 2014·Journal of Visualized Experiments : JoVE·Rivkeh Y HaryonoRussell S J Keast
Feb 18, 2015·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A SayedN A Khan
Jan 23, 2016·The Tohoku Journal of Experimental Medicine·Masanobu AsanoTada-Aki Kudo
Jan 28, 2016·Obesity·Lisa P NewmanRussell S J Keast
May 8, 2016·Progress in Lipid Research·Dongli LiuRussell Keast
Jun 18, 2016·Journal of the American College of Nutrition·Kate HaringtonBernard Joseph Venn
Jul 21, 2017·Nutrients·Andrew CostanzoRussell Keast
Apr 17, 2018·The American Journal of Clinical Nutrition·Andrew CostanzoRussell Keast

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May 26, 2021·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Fiona Harnischfeger, Robin Dando

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