A feasible study on using multiplexed sensitivity-encoding to reduce geometric distortion in diffusion-weighted echo planar imaging

Magnetic Resonance Imaging
Xinyuan ChenJianrong Dai

Abstract

Single-shot (SS) echo planar imaging (EPI) is commonly used for diffusion-weighted imaging (DWI) in radiation treatment planning. The geometric distortion of single-shot diffusion-weighted EPI (SS-DWEPI) limits its utility in precision radiotherapy. We aimed to investigate the use of multiplexed sensitivity-encoding DWEPI (MUSE-DWEPI) to reduce the geometric distortions to allow its use in brain radiotherapy. In a phantom study, phantom diameters measured using MUSE-DWEPI and SS-DWEPI were compared and the percentages of geometric distortion (%GD) were calculated. The shifting vectors of control points were also plotted and calculated. In a patient study, ten patients (six with post-surgery glioma, four with brain metastases) requiring MRI were enrolled, and the image distortion levels in SS-DWEPI and MUSE-DWEPI were compared using T2 Periodically Rotated Overlapping Parallel Lines with Enhanced Reconstruction (T2 PROPELLER) images as the reference. The tumor targets and four brain regions were delineated based on T2 PROPELLER, SS-DWEPI, and MUSE-DWEPI, using the Dice similarity coefficient (DSC) and the Hausdorff distance (HD) to quantify the level of geometric distortion. In the phantom study, the most prominent image distort...Continue Reading

Citations

Jun 26, 2021·Journal of Magnetic Resonance Imaging : JMRI·Hing-Chiu ChangKeith Wan-Hang Chiu

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