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A filter-flow perspective of hematogenous metastasis offers a non-genetic paradigm for personalized cancer therapy

bioRxiv

Nov 7, 2013

Jacob G. ScottPhilip Gerlee

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Abstract

Background: Research into mechanisms of hematogenous metastasis has largely become genetic in focus, attempting to understand the molecular basis of `seed-soil' relationships. However, preceding this biological mechanism is the physical process of dissemination of circulating tumour cel...read more

Mentioned in this Paper

Gene Flow
Entire Capillary Blood Vessel (Organ)
Evaluation
Blood Capillaries
Clinical Trials
Organ
Fruit
Classification
Lung Problem
Clinician
9
3
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  • A filter-flow perspective of hematogenous metastasis offers a non-genetic paradigm for personalized cancer therapy

    bioRxiv

    Nov 7, 2013

    Jacob G. ScottPhilip Gerlee

    PMID: 990000125

    DOI: 10.1101/000125

    Abstract

    Background: Research into mechanisms of hematogenous metastasis has largely become genetic in focus, attempting to understand the molecular basis of `seed-soil' relationships. However, preceding this biological mechanism is the physical process of dissemination of circulating tumour cel...read more

    Mentioned in this Paper

    Gene Flow
    Entire Capillary Blood Vessel (Organ)
    Evaluation
    Blood Capillaries
    Clinical Trials
    9
    3

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