A finite element method to correct deformable image registration errors in low-contrast regions.

Physics in Medicine and Biology
Hualiang ZhongIndrin J Chetty

Abstract

Image-guided adaptive radiotherapy requires deformable image registration to map radiation dose back and forth between images. The purpose of this study is to develop a novel method to improve the accuracy of an intensity-based image registration algorithm in low-contrast regions. A computational framework has been developed in this study to improve the quality of the 'demons' registration. For each voxel in the registration's target image, the standard deviation of image intensity in a neighborhood of this voxel was calculated. A mask for high-contrast regions was generated based on their standard deviations. In the masked regions, a tetrahedral mesh was refined recursively so that a sufficient number of tetrahedral nodes in these regions can be selected as driving nodes. An elastic system driven by the displacements of the selected nodes was formulated using a finite element method (FEM) and implemented on the refined mesh. The displacements of these driving nodes were generated with the 'demons' algorithm. The solution of the system was derived using a conjugated gradient method, and interpolated to generate a displacement vector field for the registered images. The FEM correction method was compared with the 'demons' algori...Continue Reading

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Citations

Sep 2, 2014·Computer Methods and Programs in Biomedicine·Herng-Hua Chang, Chih-Yuan Tsai
Aug 24, 2013·Zeitschrift für medizinische Physik·Daniella FabriMichael Figl
Mar 20, 2016·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Mohamed NassefRenaud de Crevoisier
Jan 8, 2015·Medical Physics·Ola Weistrand, Stina Svensson
Nov 11, 2016·IEEE Transactions on Medical Imaging·You ZhangJing Wang
Nov 22, 2013·Journal of Applied Clinical Medical Physics·Nick StanleyHualiang Zhong
Apr 2, 2015·Physics in Medicine and Biology·Navid SamavatiKristy Brock
Nov 5, 2015·Physics in Medicine and Biology·Joubin Nasehi TehraniJing Wang
Jun 29, 2013·Physics in Medicine and Biology·S ReaungamornratR H Taylor
Mar 18, 2015·Physics in Medicine and Biology·Hualiang ZhongIndrin J Chetty
Aug 9, 2020·Physics in Medicine and Biology·Cornel ZachiuMario G Ries

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