A fluorescent switchable AIE probe for selective imaging of dipeptidyl peptidase-4 in vitro and in vivo and its application in screening DPP-4 inhibitors

Chemical Communications : Chem Comm
Yi WangXiaoping Zhao

Abstract

A novel fluorescent probe for in vitro and in vivo imaging of dipeptidyl peptidase-4 (DPP-4) was designed and synthesized. This probe is successfully utilized to screen DPP-4 inhibitors in living 3T3-L1 cells and zebrafish, which provides a novel approach for the discovery of anti-diabetes drugs.

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Citations

Jun 19, 2013·Current Opinion in Chemical Biology·Christoph J Fahrni
Jul 24, 2018·Chemical Communications : Chem Comm·Jie XingAiguo Wu
Dec 7, 2018·Chemical Society Reviews·Junji ZhangHe Tian
Jan 3, 2019·Chemistry : a European Journal·Sheng XieBen Zhong Tang
Jan 4, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Xiumei GuoHong Gao
Sep 7, 2016·Small·Yi-Feng WangXing-Jie Liang
May 27, 2021·Analytical Methods : Advancing Methods and Applications·Jing ZhangLi-Wei Zou
Dec 13, 2017·ACS Applied Materials & Interfaces·Jie ShiZhen Li
Nov 16, 2017·ACS Applied Materials & Interfaces·Ju MeiHe Tian

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