PMID: 8963477Jun 1, 1996Paper

A focal stress gradient-dependent mass transfer mechanism for atherogenesis in branching arteries

Medical Engineering & Physics
M LeiG A Truskey

Abstract

A new arterial wall permeability function, based on the local wall shear stress gradient, has been developed and employed to simulate enhanced low density lipoprotein transfer across the endothelium. the atherosclerotic model used is that of the aorto-celiac junction of rabbits. The experimentally validated computer simulation model for convection mass transfer provides further evidence that the wall shear stress gradient is a reliable predictor of critical atherogenic sites in branching arteries. Some of the underlying biological aspects of atherogenesis due to locally significant and sustained wall shear stress gradient values are briefly discussed.

References

Nov 11, 1992·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·N DePaolaC F Dewey
Aug 1, 1992·Journal of Biomechanical Engineering·R M Nerem
Aug 1, 1992·Journal of Biomechanical Engineering·A I BarakatC K Colton
Aug 11, 1992·Journal of Biomechanical Engineering·R L SatcherC F Dewey
Aug 1, 1991·Journal of Biomechanical Engineering·C KleinstreuerJ P Archie
Jan 1, 1990·Journal of Biomechanics·M NazemiJ P Archie
Feb 1, 1985·Annals of Surgery·M E DeBakeyD H Glaeser
Apr 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·P F DaviesM A Gimbrone
May 1, 1985·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·D N KuS Glagov
Nov 1, 1985·Journal of Biomechanical Engineering·M J Levesque, R M Nerem
Apr 1, 1970·The Journal of Clinical Investigation·S ChienJ F Bertles
May 1, 1968·Canadian Anaesthetists' Society Journal·H B AronsonB Etsten
Dec 1, 1993·Atherosclerosis·M H Friedman, D L Fry
Nov 1, 1993·Journal of Biomechanical Engineering·S Weinbaum, S Chien
Feb 1, 1994·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·R A HerrmannG A Truskey
Feb 1, 1993·Circulation Research·P F Davies, S C Tripathi
Aug 1, 1995·Journal of Biomechanical Engineering·M LeiG A Truskey
Sep 1, 1991·Biotechnology and Bioengineering·M U NollertL V McIntire

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Citations

Jan 4, 2006·Annals of Biomedical Engineering·David A Steinman, Charles A Taylor
Feb 21, 2009·Annals of Biomedical Engineering·Leonid GoubergritsHans-Christian Hege
Jun 13, 2009·Annals of Biomedical Engineering·Robert W LyczkowskiSanjeev G Shroff
May 25, 2010·Annals of Biomedical Engineering·Foad KabinejadianYong Seng Tan
Jul 21, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Bogdan Ene-Iordache, Andrea Remuzzi
Oct 17, 2001·Journal of Biomechanical Engineering·E A Finol, C H Amon
Aug 1, 1995·Journal of Biomechanical Engineering·M LeiG A Truskey
May 20, 2009·Journal of Biomechanical Engineering·Sang-Wook LeeDavid A Steinman
Apr 10, 2012·Journal of Biomechanical Engineering·Timothy J GundertJohn F LaDisa
Dec 18, 2013·Biomedical Engineering Online·Dhanjoo N Ghista, Foad Kabinejadian
Oct 18, 2008·Biomedical Engineering Online·Johannes V SoulisGeorge E Louridas
Jan 6, 2012·Computer Methods and Programs in Biomedicine·Amal Ahmed OwidaYos S Morsi
May 10, 2011·Journal of Biomechanics·Thanapong ChaichanaJames Jewkes
Mar 10, 2010·Computers in Biology and Medicine·Jonathan Murphy, Fergal Boyle
Feb 7, 2009·Journal of Biomechanics·Yunlong HuoGhassan S Kassab
Jan 30, 2015·Medical Engineering & Physics·Jonas LantzMatts Karlsson
Jul 14, 2005·Journal of Medical Engineering & Technology·X-M Li, S E Rittgers
Dec 12, 2012·Stroke; a Journal of Cerebral Circulation·Yoichi MiuraWaro Taki
Jul 23, 2014·Journal of Biomechanical Engineering·Xinzhou XieJingmin Zhou
Sep 11, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Yunlong HuoGhassan S Kassab
Oct 17, 2009·The Open Cardiovascular Medicine Journal·J SoulisD Mikhailidis

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