A follow up study of patients with paraneoplastic neurological disease in the United Kingdom

Journal of Neurology, Neurosurgery, and Psychiatry
P M CandlerJ H Rees

Abstract

To examine the range of clinical phenotypes, tumour associations, relevant investigations, response to therapy and outcome in a large series of non-selected patients with paraneoplastic neurological disease (PND) affecting the central nervous system (CNS) in the United Kingdom. Data were obtained on patients either through direct referral or through the British Neurological Surveillance Unit (BNSU) from February 2000 to January 2001. Physicians were asked to supply information about age and sex of patients, presenting neurological syndromes, the basis of the diagnosis of PND, any associated malignancy, and treatment. Case notes were reviewed and follow up data obtained where possible one year after notification. A total of 63 patients (48 females, 15 males) were identified, 48 through the BNSU and 15 through direct referral. Of these 52 were diagnosed as having definite PND, 10 probable PND, and 1 possible PND. The median age of onset of PND was 66 years (range 30-80 years) and only 7 patients (11%) were less than 50 years at presentation. In 53 patients (84%) the PND preceded the diagnosis of cancer. Paraneoplastic sensory neuronopathy, paraneoplastic encephalomyelitis, and paraneoplastic cerebellar degeneration (PCD) were the...Continue Reading

References

Sep 1, 1991·Journal of Neurology, Neurosurgery, and Psychiatry·G M ElringtonJ Newsom-Davis
Oct 1, 1988·Annals of Neurology·N E AndersonJ B Posner
Sep 1, 1965·Brain : a Journal of Neurology·P B CroftP C Wilkinson
Aug 15, 1998·Clinical Oncology : a Journal of the Royal College of Radiologists·M FarisP Barrett-Lee
May 17, 2001·Brain : a Journal of Neurology·F GrausJ Y Delattre
Aug 9, 2001·Acta Neurologica Scandinavica·P StouracV Palyza
May 24, 2003·Brain : a Journal of Neurology·Setareh Shams'iliPeter Sillevis Smitt

❮ Previous
Next ❯

Citations

Jul 25, 2009·Journal of Neurology·K BürkR Voltz
Aug 30, 2008·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Steven Vernino
Sep 21, 2013·Cancer Metastasis Reviews·David Tarin
Apr 26, 2006·Current Neurology and Neuroscience Reports·Steven Vernino
Feb 14, 2006·Current Neurology and Neuroscience Reports·Myrna R Rosenfeld, Josep Dalmau
Sep 16, 2010·Current Treatment Options in Neurology·John E Greenlee
Jan 15, 2013·Current Treatment Options in Neurology·John E Greenlee
Nov 19, 2008·Parkinsonism & Related Disorders·Thomas Klockgether
Sep 3, 2010·Journal of Clinical Neuromuscular Disease·B Jane Distad, Michael D Weiss
Jun 7, 2012·Nuclear Medicine Communications·Sriram VaidyanathanSai Han
Jun 12, 2013·Practical Neurology·Hilary Anne ArcherNicola Jane Giffin
Sep 23, 2014·Current Problems in Cancer·Samuel MartelGiovanna Speranza
Mar 18, 2008·The British Journal of Radiology·D W Anderson, A Borsaru
Oct 1, 2012·Clinical Journal of Gastroenterology·Takashi TaketaHisashi Onodera
Apr 25, 2007·Leukemia & Lymphoma·Hendrik-Tobias ArkenauDavid Cunningham
Oct 4, 2005·Expert Opinion on Biological Therapy·Edward J Dropcho
Jan 11, 2011·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Michiko AsanoTakumi Kishimoto
Mar 4, 2006·Clinical Lung Cancer·Shulian WangRitsuko R Komaki
Apr 3, 2007·La Presse médicale·Jean-Christophe Antoine, Jean-Philippe Camdessanché
Feb 28, 2007·Neurologic Clinics·Steven Vernino, Gil I Wolfe
Mar 31, 2009·International Journal of Cancer. Journal International Du Cancer·Michael E BenrosPreben B Mortensen
Mar 29, 2013·Muscle & Nerve·Christina N FournierJayashri Srinivasan
Aug 14, 2013·Clinical and Experimental Immunology·F Leypoldt, K-P Wandinger
Sep 9, 2016·Annals of Clinical and Translational Neurology·Anand Venkatraman, Puneet Opal
Nov 2, 2016·Experimental Hematology & Oncology·Ibrahim Fanous, Patrick Dillon
Jun 30, 2007·Molekuliarnaia genetika, mikrobiologiia i virusologiia·P V BelousovD V Kuprash
May 14, 2005·Current Opinion in Neurology·Edward J Dropcho
Sep 13, 2005·Current Opinion in Neurology·Stacy A Rudnicki, Josep Dalmau
Sep 18, 2018·Current Neuropharmacology·Hiroshi MitomaChristiane S Hampe
Dec 23, 2017·CNS & Neurological Disorders Drug Targets·Marios Hadjivassiliou
May 2, 2018·Neurology·Sudeepta DandapatJames Gilchrist
Feb 19, 2005·Journal of Neuro-oncology·Joachim M Baehring
Nov 13, 2015·Cerebellum & Ataxias·Hiroshi MitomaJérôme Honnorat
Nov 27, 2014·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Jacqueline J GreeneAkihiro J Matsuoka
Jul 3, 2017·Pain and Therapy·Panagiotis ZisMarios Hadjivassiliou
Nov 9, 2017·Breast Cancer Research and Treatment·Brittany L MurphyElizabeth B Habermann
Oct 7, 2008·Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine·Toru Kawanani, Takeo Katou

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Related Papers

Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Hitoshi MurakamiToshio Imada
Journal of Neurology, Neurosurgery, and Psychiatry
F GrausR Voltz
© 2021 Meta ULC. All rights reserved