PMID: 8801090Feb 1, 1996Paper

A four-year prospective study on microbial ecology of explanted prosthetic hips in 52 patients with "aseptic" prosthetic joint loosening

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
F Perdreau-RemingtonG Pulverer


The bacteriology of explanted prosthetic hips and surrounding soft tissue was studied in 52 patients undergoing surgical revision for joint loosening. In a prospective four-year study, positive bacterial cultures were recorded in 34 (76%) patients. Coagulase-negative staphylococci were the predominant isolates, and 11 patients (33%) had more than three organisms isolated, 7 (20%) had two only, and 11 (33%) had one species. Among the 23 patients from whom specimens from all 11 predetermined anatomic sites were cultured, the highest frequency of positive cultures (52% and 47%) came from the shaft and capsular tissue, respectively. Organisms were less frequently recovered from the cement and acetabulum (13% and 4%, respectively). Using molecular typing in eight patients with paired isolates of the same species, clonal identity was found in four. An additional patient underwent a second revision for loosening 17 months after the first revision and the same clone of Staphylococcus epidermidis was isolated on both occasions.


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Oct 1, 1989·The Journal of Diabetic Complications·T B WiegmannW V Moore
May 1, 1989·Antimicrobial Agents and Chemotherapy·G M Dickinson, A L Bisno
Mar 1, 1994·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·F Schumacher-PerdreauG Pulverer
Feb 1, 1994·Acta Orthopaedica Scandinavica·W H Harris

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