PMID: 12763664May 24, 2003Paper

A functionalized cobalt(III) mixed-polypyridyl complex as a newly designed DNA molecular light switch

Journal of Inorganic Biochemistry
Qian-Ling ZhangLiang-Nian Ji

Abstract

The ligand ODHIP (3,4-dihydroxyl-imidazo[4,5-f][1,10]phenanthroline) and its cobalt(III) complex [Co(bpy)(2)(ODHIP)](3+) were synthesized and characterized. Binding of this complex with calf thymus DNA has been investigated by spectroscopic methods and viscosity. The experimental results indicated that the complex bound to DNA by intercalation. In Tris buffer, the complex could emit relatively weak luminescence. After binding to DNA, the notable enhancement was observed. However, when the Cu(2+) was further added, the luminescence decreased gradually and disappeared after the equimolar concentrations of Cu(2+) was added, which exhibited the "off-on-off" properties of molecular light switch.

Citations

Feb 7, 2012·Nucleosides, Nucleotides & Nucleic Acids·Chittanahalli N SudhamaniD Girija
Aug 2, 2016·Inorganic Chemistry·Qian YangSong Gao
Apr 16, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·Qian YangSong Gao
Nov 13, 2012·Dalton Transactions : an International Journal of Inorganic Chemistry·Jennifer M HopeStephen J Lippard
Mar 2, 2011·Dalton Transactions : an International Journal of Inorganic Chemistry·Sethu RamakrishnanMallayan Palaniandavar
Dec 18, 2013·Dalton Transactions : an International Journal of Inorganic Chemistry·Mei-Jin LiGuo-Nan Chen
Aug 4, 2005·Journal of the American Chemical Society·Yao LiuClaudia Turro
Jan 9, 2008·Journal of the American Chemical Society·Daniel A LuttermanClaudia Turro

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