A further validation of subareolar injection technique for breast sentinel lymph node biopsy

Annals of Surgical Oncology
Giovanni D'EreditaTommaso Berardi

Abstract

In this study we performed subdermal injection of (99m)Tc-labeled albumin combined with subareolar (SA) injection of blue dye, and we compared this technique with two techniques previously used in terms of the success of sentinel lymph node (SLN) identification, false-negative (FN) rate, and the overall accuracy and sensitivity of the three procedures. In all patients we performed a complete axillary lymph node dissection. From January 1999 to September 2004, a total of 195 patients with localized breast cancer were treated. Patients were subdivided into three groups. In patients in group 1 (n = 115; January 1999 to December 2001), lymphoscintigraphy together with injection of vital dye was performed; in group 2 (n = 40; January to October 2002), SA injection of blue dye alone was performed; and in group 3 (n = 40; November 2002 to September 2004), SA injection of blue dye and subdermal injection of radioisotope was performed. The success rate of identifying an SLN by a combination of the two techniques was 95% in group 1 and 100% in group 3. The FN rate was 9% in group 1 and 0% in groups 2 and 3. The overall accuracy of lymphatic mapping was 97% in group 1 and 100% in groups 2 and 3. Sensitivity was 91% in group 1 and 100% in ...Continue Reading

References

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Citations

Oct 24, 2009·The Breast : Official Journal of the European Society of Mastology·David Martinez-RamosJose Luis Salvador-Sanchis
Jun 23, 2009·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S K SomasundaramM R S Keshtgar
Feb 13, 2007·The Breast : Official Journal of the European Society of Mastology·Giovanni D'Eredita'Tommaso Berardi

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