A gas chromatography-thermal conductivity detection method for helium detection in postmortem blood and tissue specimens

Journal of Analytical Toxicology
Jason E SchaffLaureen Marinetti

Abstract

In cases of death by inert gas asphyxiation, it can be difficult to obtain toxicological evidence supporting assignment of a cause of death. Because of its low mass and high diffusivity, and its common use as a carrier gas, helium presents a particular challenge in this respect. We describe a rapid and simple gas chromatography-thermal conductivity detection method to qualitatively screen a variety of postmortem biological specimens for the presence of helium. Application of this method is demonstrated with three case examples, encompassing an array of different biological matrices.

References

Aug 29, 2002·The American Journal of Forensic Medicine and Pathology·Russel D Ogden, Rae H Wooten
Nov 25, 2003·The American Journal of Forensic Medicine and Pathology·Kenneth E GallagherPaul F Mellen
Jun 16, 2007·Wiener klinische Wochenschrift·Martin Grassberger, Astrid Krauskopf
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Nov 29, 2007·The American Journal of Forensic Medicine and Pathology·Corinna Ariane Schön, Thomas Ketterer
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Citations

Jan 9, 2014·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·S A Handley, R J Flanagan
Sep 25, 2012·Forensic Science International : Synergy·Frank MusshoffBurkhard Madea
Aug 25, 2015·Forensic Science International : Synergy·Roelof OostingMiranda Verschraagen
Apr 27, 2016·International Journal of Legal Medicine·S MalbranqueV Varlet
Feb 9, 2019·International Journal of Legal Medicine·Vincent VarletS Grabherr

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