A Gc silent allele encountered in a paternity case

Human Heredity
K SuzukiH Matsumoto

Abstract

A father-child incompatibility only in the Gc system was detected in a paternity case tested at our laboratory. Quantitative determination revealed that the Gc level in the two individuals was less than 50% of the normal mean value. Evaluation of the probability calculation for the putative father using all other markers showed that he was the biological father with a very high probability. Thus it was concluded that a silent allele Gc*QO was transmitted from the father to the child.

Citations

Sep 2, 1998·Proceedings of the National Academy of Sciences of the United States of America·D E PromislowL Pearse

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