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A general unified framework to assess the sampling variance of heritability estimates using pedigree or marker-based relationships

Genetics

Jan 1, 2015

Peter M. Visscher, Michael E. Goddard

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Abstract

Heritability is a population parameter of importance in evolution, plant and animal breeding, and human medical genetics. It can be estimated using pedigree designs and, more recently, using relationships estimated from markers. We derive the sampling variance of the estimate of heritab...read more

Mentioned in this Paper

Sampling Studies
Genetic Pedigree
Quantitative Trait, Heritable
Likelihood Functions
Genetic Markers
Animal Breeding
Variation (Genetics)
Genome, Human
Medical Genetics Specialty
Genealogical Tree
4
85
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  • A general unified framework to assess the sampling variance of heritability estimates using pedigree or marker-based relationships

    Genetics

    Jan 1, 2015

    Peter M. Visscher, Michael E. Goddard

    PMID: 25361897

    DOI: 10.1534/genetics.114.171017

    Abstract

    Heritability is a population parameter of importance in evolution, plant and animal breeding, and human medical genetics. It can be estimated using pedigree designs and, more recently, using relationships estimated from markers. We derive the sampling variance of the estimate of heritab...read more

    Mentioned in this Paper

    Sampling Studies
    Genetic Pedigree
    Quantitative Trait, Heritable
    Likelihood Functions
    Genetic Markers
    4
    85

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