A genetic mechanism for female-limited Batesian mimicry in Papilio butterfly

Nature Genetics
Hideki NishikawaHaruhiko Fujiwara

Abstract

In Batesian mimicry, animals avoid predation by resembling distasteful models. In the swallowtail butterfly Papilio polytes, only mimetic-form females resemble the unpalatable butterfly Pachliopta aristolochiae. A recent report showed that a single gene, doublesex (dsx), controls this mimicry; however, the detailed molecular mechanisms remain unclear. Here we determined two whole-genome sequences of P. polytes and a related species, Papilio xuthus, identifying a single ∼130-kb autosomal inversion, including dsx, between mimetic (H-type) and non-mimetic (h-type) chromosomes in P. polytes. This inversion is associated with the mimicry-related locus H, as identified by linkage mapping. Knockdown experiments demonstrated that female-specific dsx isoforms expressed from the inverted H allele (dsx(H)) induce mimetic coloration patterns and simultaneously repress non-mimetic patterns. In contrast, dsx(h) does not alter mimetic patterns. We propose that dsx(H) switches the coloration of predetermined wing patterns and that female-limited polymorphism is tightly maintained by chromosomal inversion.

References

Mar 16, 1972·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·C A Clarke, P M Sheppard
Dec 1, 1980·Developmental Biology·H F Nijhout
Mar 26, 2003·Genome Research·Michael BrudnoSerafim Batzoglou
Nov 21, 1996·Nature·P M BrakefieldS B Carroll
Aug 13, 2003·Bioinformatics·Fredrik Ronquist, John P Huelsenbeck
Feb 17, 2005·BMC Bioinformatics·Guy St C Slater, Ewan Birney
Nov 9, 2006·BMC Developmental Biology·Antónia MonteiroDiane Ramos
Mar 6, 2009·Genome Biology·Ben LangmeadSteven L Salzberg
Jun 10, 2009·Bioinformatics·Heng LiUNKNOWN 1000 Genome Project Data Processing Subgroup
Jun 26, 2009·Evolution; International Journal of Organic Evolution·Krushnamegh Kunte
Jan 1, 2007·Journal of Insect Science·Kyle GoldenAntónia Monteiro
Apr 30, 2011·BMC Bioinformatics·Marcus LechnerSonja J Prohaska
May 17, 2011·Nature Biotechnology·Manfred G GrabherrAviv Regev
Aug 16, 2011·Nature·Mathieu JoronRichard H ffrench-Constant
Oct 8, 2011·PloS One·Junichi YamaguchiHaruhiko Fujiwara
Mar 6, 2012·Nature Methods·Ben Langmead, Steven L Salzberg
Dec 20, 2012·Development·Toshiya Ando, Haruhiko Fujiwara
Jan 19, 2013·Molecular Biology and Evolution·Kazutaka Katoh, Daron M Standley
Mar 7, 2014·Nature·David W Loehlin, Sean B Carroll
Mar 7, 2014·Nature·K KunteM R Kronforst

❮ Previous
Next ❯

Citations

Mar 10, 2016·Genome Biology and Evolution·Qian CongNick V Grishin
Aug 28, 2015·BMC Genomics·Qian CongNick V Grishin
Jun 5, 2015·Proceedings. Biological Sciences·Tasuku Kitamura, Michio Imafuku
Jun 17, 2015·Current Biology : CB·Tom BookerDeborah Charlesworth
May 29, 2016·BMC Evolutionary Biology·Muhammad Z AhmedAkito Y Kawahara
Oct 11, 2016·Current Opinion in Insect Science·Haruhiko Fujiwara, Hideki Nishikawa
Oct 11, 2016·Current Opinion in Insect Science·Nicola J Nadeau
Jul 20, 2016·Proceedings of the National Academy of Sciences of the United States of America·Scott V EdwardsCraig Moritz
Sep 14, 2016·Current Biology : CB·James Mallet, Hopi E Hoekstra
Feb 9, 2017·Molecular Ecology·Violaine LlaurensMathieu Joron
Apr 22, 2017·The Journal of Heredity·Joji M Otaki, Wataru Taira
May 10, 2017·GigaScience·Reuben W NowellMark Blaxter
Jan 10, 2018·Evolution; International Journal of Organic Evolution·Baharan KazemiOlof Leimar
Nov 4, 2017·Journal of Experimental Botany·Christian KappelMichael Lenhard
Aug 9, 2017·Journal of Evolutionary Biology·M RavinetA M Westram
Sep 16, 2017·Wiley Interdisciplinary Reviews. Developmental Biology·Riddhi DeshmukhKrushnamegh Kunte
Oct 27, 2018·Genome Génome / Conseil National De Recherches Canada·Qian Cong, Nick V Grishin
Dec 12, 2018·Nature Ecology & Evolution·Ningning WuShuai Zhan
Jan 13, 2018·Proceedings. Biological Sciences·Emily L BehrmanPaul S Schmidt
Jan 16, 2019·Development, Growth & Differentiation·Toshiya Ando, Teruyuki Niimi
Feb 10, 2019·Insect Molecular Biology·T K SuzukiH Sezutsu
Sep 12, 2015·Nature Communications·Xueyan LiWen Wang
Mar 31, 2015·Nature Genetics·James Mallet
Jul 22, 2016·Proceedings. Biological Sciences·David A S SmithRichard Ffrench-Constant
Sep 19, 2019·Nature Ecology & Evolution·Chu-Yu YeLongjiang Fan
May 24, 2019·Insect Molecular Biology·F LiJ R Walters
Nov 2, 2019·Science·Nathaniel B EdelmanJames Mallet
Sep 5, 2019·Proceedings. Biological Sciences·Shahab ZareyanChristoph Hauert
Apr 30, 2020·Proceedings. Biological Sciences·Martijn J T N TimmermansAlfried P Vogler
Mar 13, 2020·G3 : Genes - Genomes - Genetics·Kumar Saurabh SinghManmohan D Sharma

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
C A Clarke, P M Sheppard
Nature
Krushnamegh KunteMarcus R Kronforst
© 2022 Meta ULC. All rights reserved