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A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture

bioRxiv

May 22, 2014

Henriette O'GeenDavid J Segal

Abstract

Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided nucleases have gathered considerable excitement as a tool for genome engineering. However, questions remain about the specificity of their target site recognition. Most previous studies have examined predicted ...read more

Mentioned in this Paper

SNURF gene
Computed (Procedure)
Adjacent
Site
Maintenance of Crispr Repeat Elements
DNA Cleavage
Mus
Palindromic Repeat Sequences
Genome-Wide Association Study
Ribonucleases
9
49
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A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture

bioRxiv

May 22, 2014

Henriette O'GeenDavid J Segal

PMID: 990005413

DOI: 10.1101/005413

Abstract

Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided nucleases have gathered considerable excitement as a tool for genome engineering. However, questions remain about the specificity of their target site recognition. Most previous studies have examined predicted ...read more

Mentioned in this Paper

SNURF gene
Computed (Procedure)
Adjacent
Site
Maintenance of Crispr Repeat Elements
DNA Cleavage
Mus
Palindromic Repeat Sequences
Genome-Wide Association Study
Ribonucleases
9
49

Similar Papers Found In These Feeds

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