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A genome wide dosage suppressor network reveals genomic robustness

Nucleic Acids Research

Dec 3, 2016

Biranchi PatraAnimesh Ray

Abstract

Genomic robustness is the extent to which an organism has evolved to withstand the effects of deleterious mutations. We explored the extent of genomic robustness in budding yeast by genome wide dosage suppressor analysis of 53 conditional lethal mutations in cell division cycle and RNA ...read more

Mentioned in this Paper

Saccharomyces cerevisiae Proteins
Genome-Wide Association Study
RNA Polymerase II
Biochemical Pathway
CFC1 gene
Abnormal Degeneration
Gene Dosage
RNA Chemical Synthesis
Genome
Genes
4
23
Paper Details
References
  • References77
  • Citations2
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  • References77
  • Citations2
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A genome wide dosage suppressor network reveals genomic robustness

Nucleic Acids Research

Dec 3, 2016

Biranchi PatraAnimesh Ray

PMID: 27899637

DOI: 10.1093/nar/gkw1148

Abstract

Genomic robustness is the extent to which an organism has evolved to withstand the effects of deleterious mutations. We explored the extent of genomic robustness in budding yeast by genome wide dosage suppressor analysis of 53 conditional lethal mutations in cell division cycle and RNA ...read more

Mentioned in this Paper

Saccharomyces cerevisiae Proteins
Genome-Wide Association Study
RNA Polymerase II
Biochemical Pathway
CFC1 gene
Abnormal Degeneration
Gene Dosage
RNA Chemical Synthesis
Genome
Genes
4
23

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Structural Biology: Biophysics

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Eukaryotic RNA Polymerase II (Keystone)

RNA polymerase II (RNAP II) is a 550 kDa multiprotein complex composed of 12 subunits. Here is the latest research on RNAP II and its role it regulating transcription and transcription-coupled recombination repair.

Related Papers

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme

Genome analysis of budding yeast

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzymeFebruary 10, 1998
Y Murakami
Nucleic Acids Research

Cell cycle control of DNA synthesis in budding yeast

Nucleic Acids ResearchMay 25, 1992
L H Johnston, N F Lowndes
Paper Details
References
  • References77
  • Citations2
12345...
  • References77
  • Citations2
1
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