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A genome wide dosage suppressor network reveals genetic robustness and a novel mechanism for Huntington’s disease

bioRxiv

Nov 12, 2013

Biranchi PatraAnimesh Ray

Abstract

Mutational robustness is the extent to which an organism has evolved to withstand the effects of deleterious mutations. We explored the extent of mutational robustness in the budding yeast by genome wide dosage suppressor analysis of 53 conditional lethal mutations in cell division cycl...read more

Mentioned in this Paper

Huntington Disease
Mitotic Sister Chromatid Cohesion
Visual Suppression
Mutant Proteins
RNA Chemical Synthesis
Complex (molecular entity)
Biochemical Pathway
Biologic Degeneration
Nerve Degeneration
Organism
9
4
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A genome wide dosage suppressor network reveals genetic robustness and a novel mechanism for Huntington’s disease

bioRxiv

Nov 12, 2013

Biranchi PatraAnimesh Ray

PMID: 990000265

DOI: 10.1101/000265

Abstract

Mutational robustness is the extent to which an organism has evolved to withstand the effects of deleterious mutations. We explored the extent of mutational robustness in the budding yeast by genome wide dosage suppressor analysis of 53 conditional lethal mutations in cell division cycl...read more

Mentioned in this Paper

Huntington Disease
Mitotic Sister Chromatid Cohesion
Visual Suppression
Mutant Proteins
RNA Chemical Synthesis
Complex (molecular entity)
Biochemical Pathway
Biologic Degeneration
Nerve Degeneration
Organism
9
4

Similar Papers Found In These Feeds

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