A genome-wide identification and classification of basic helix-loop-helix genes in the jewel wasp, Nasonia vitripennis (Hymenoptera: Pteromalidae)

Genome Génome / Conseil National De Recherches Canada
Xiao-Ting LiuKe-Ping Chen

Abstract

Basic helix-loop-helix (bHLH) proteins are highly conserved DNA-binding transcription factors of a large superfamily. Animal bHLH proteins play important regulatory roles in various developmental processes such as neurogenesis, myogenesis, heart development, and hematopoiesis. The jewel wasp (Nasonia vitripennis) is a good model organism of hymenoptera insects for studies of developmental and evolutionary genetics. In this study, we identified 48 bHLH genes in the genome of N. vitripennis. According to phylogenetic analysis, based on N. vitripennis bHLH (NvbHLH) motif sequences and structural domain distribution in their full-length protein sequences, the identified NvbHLH genes were classified into 36 bHLH families with 19, 12, 9, 1, 6, and 1 member(s) in groups A, B, C, D, E, and F, respectively. Our classification to the identified NvbHLH family members confirms GenBank annotations for 21 of the 48 NvbHLH proteins and provides useful information for further characterization and annotation of the remaining 27 NvbHLH proteins. Compared to other insect species, N. vitripennis has the lowest number of bHLH family members. No NvbHLH members have been found in the families Net, MyoRa, and PTFa, while all other insect species have ...Continue Reading

References

Jan 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·C V DangG J Kato
Nov 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·R FairmanS L Brenner
May 6, 1993·Nature·A R Ferré-D'AmaréS K Burley
May 13, 1997·Proceedings of the National Academy of Sciences of the United States of America·W R Atchley, W M Fitch
Jan 20, 1999·Proceedings of the National Academy of Sciences of the United States of America·J LuE N Olson
Apr 10, 1999·Journal of Molecular Evolution·W R AtchleyA Dress
Dec 28, 1999·Molecular and Cellular Biology·M E Massari, C Murre
Jun 10, 2004·Genome Biology·Susan Jones
Jun 1, 2006·Journal of Cell Science·Nicole L Washington, Samuel Ward
Sep 28, 2007·Development Genes and Evolution·Yong WangZhu Zhi
Mar 28, 2008·Molecular Biology and Evolution·Si Quang Le, Olivier Gascuel
Mar 24, 2009·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Xiaodong ZhengKeping Chen
Nov 28, 2009·Molecular Biology and Evolution·Nuno Pires, Liam Dolan
Aug 30, 2011·Journal of Insect Science·Chun-Wang DangMin Guo

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