A geodesic deformable model for automatic segmentation of image sequences applied to radiation therapy.

International Journal of Computer Assisted Radiology and Surgery
G BuenoJ M Delgado

Abstract

Organ motion should be taken into account for image-guided fractionated radiotherapy. A deformable segmentation and registration method was developed for inter-and intra-fraction organ motion planning and evaluation. Energy minimizing active models were synthesized for tracking a set of organs delineated by regions of interest (ROI) in radiotherapy treatment. The initial model consists of a surface deformed to match the ROI contour by geometrical properties, following a heat flow model. The deformable segmentation model was tested using a Shepp-Logan head CT simulation, and different quantitative metrics were applied such as ROC analysis, Jaccard index, Dice coefficient and Hausdorff distance. Experimental evaluation of automated versus manual segmentation was done for the cardiac, thoracic and pelvic regions. The method has been quantitatively validated, obtaining an average of 93.3 and 99.2% for the sensitivity and specificity, respectively, 90.79% for the Jaccard index, 95.15% for the Dice coefficient and 0.96% mm for the Hausdorff distance. Model-based deformable segmentation was developed and tested for image-guided radiotherapy treatment planning. The method is efficient, robust and has sufficient accuracy for 2D CT data ...Continue Reading

References

Jun 23, 2000·International Journal of Radiation Oncology, Biology, Physics·M van HerkJ V Lebesque
May 8, 2001·The British Journal of Radiology·M MazonakisN Gourtsoyiannis
Jan 24, 2003·Journal of Applied Clinical Medical Physics·Dawn C CollierGeorge Starkschall
Mar 11, 2004·The British Journal of Radiology·J M Wilkinson
Nov 30, 2004·Medical Image Analysis·A TsaiA Willsky
Dec 8, 2005·Physics in Medicine and Biology·Mark FoskeySarang Joshi
Aug 19, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ludvig Paul MurenDuncan McLaren
Feb 2, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Linda van de BuntUulke A van der Heide
Apr 28, 2009·International Journal of Radiation Oncology, Biology, Physics·Peter JenkinsRichard Kinder
Aug 22, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ellen M KerkhofJan J W Lagendijk
Apr 1, 2005·Mathematical Biosciences and Engineering : MBE·Frederic GibouArthur Boyer

❮ Previous
Next ❯

Citations

Mar 2, 2013·Radiology and Oncology·Peter RogeljPrimoz Petric
Nov 30, 2012·IEEE Journal of Biomedical and Health Informatics·Changyang LiD D Feng
Aug 24, 2017·Medical Physics·Ling MaBaowei Fei
Dec 14, 2018·Physics in Medicine and Biology·Anjali BalagopalSteve Jiang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Computer Assisted Radiology and Surgery
Akinobu ShimizuKenji Shinozaki
HPB : the Official Journal of the International Hepato Pancreato Biliary Association
Fumihiko MiuraKoji Takeshita
© 2021 Meta ULC. All rights reserved