A GPCR Handles Bacterial Sensing in Chemotaxis and Phagocytosis

Developmental Cell
Hiroshi SenooMiho Iijima

Abstract

In this issue of Developmental Cell, Pan et al. (2016) identified in cells of the social amoeba Dictyostelium a G protein-coupled receptor (GPCR) that recognizes a chemoattractant secreted by bacteria. This work uncovers a mechanism by which a single GPCR mediates pseudopod extension during cell migration and bacterial engulfment.

References

Jun 1, 2006·European Journal of Cell Biology·Yogikala Prabhu, Ludwig Eichinger
Aug 24, 2006·Molecular & Cellular Proteomics : MCP·Daniel GotthardtThierry Soldati

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