A Graph-Theoretical Approach for Tracing Filamentary Structures in Neuronal and Retinal Images

IEEE Transactions on Medical Imaging
Jaydeep DeSohail Ahmed

Abstract

The aim of this study is about tracing filamentary structures in both neuronal and retinal images. It is often crucial to identify single neurons in neuronal networks, or separate vessel tree structures in retinal blood vessel networks, in applications such as drug screening for neurological disorders or computer-aided diagnosis of diabetic retinopathy. Both tasks are challenging as the same bottleneck issue of filament crossovers is commonly encountered, which essentially hinders the ability of existing systems to conduct large-scale drug screening or practical clinical usage. To address the filament crossovers' problem, a two-step graph-theoretical approach is proposed in this paper. The first step focuses on segmenting filamentary pixels out of the background. This produces a filament segmentation map used as input for the second step, where they are further separated into disjointed filaments. Key to our approach is the idea that the problem can be reformulated as label propagation over directed graphs, such that the graph is to be partitioned into disjoint sub-graphs, or equivalently, each of the neurons (vessel trees) is separated from the rest of the neuronal (vessel) network. This enables us to make the interesting conn...Continue Reading

References

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Citations

Nov 11, 2016·IEEE Transactions on Medical Imaging·Lin GuLi Cheng
Oct 11, 2017·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·Samaneh Abbasi-SureshjaniBart M Ter Haar Romeny
May 28, 2016·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Kok Haur OngWeimiao Yu
Feb 20, 2020·BMC Medical Imaging·Yanfei Guo, Yanjun Peng
May 11, 2017·Biological cybernetics·Samaneh Abbasi-SureshjaniBart Ter Haar Romeny
Jan 10, 2017·Bioinformatics·Miroslav Radojevic, Erik Meijering
Jan 1, 2018·Journal of Mathematical Imaging and Vision·Erik J BekkersJorg M Portegies
Mar 9, 2019·Frontiers in Neuroanatomy·Shiwei LiShaoqun Zeng
Aug 28, 2020·Frontiers in Neuroanatomy·Qing HuangTingwei Quan

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