A grid overlay framework for analysis of medical images and its application to the measurement of stroke lesions.

European Radiology
Paul A ArmitageJ M Wardlaw


To create and evaluate an interactive software tool for measuring imaging data in situations where hand-drawn region-of-interest measurements are unfeasible, for example, when the structure of interest is patchy with ill-defined boundaries. An interactive grid overlay software tool was implemented that enabled coding of voxels dependent on their imaging appearance with a series of user-defined classes. The Grid Analysis Tool (GAT) was designed to automatically extract quantitative imaging data, grouping the results by tissue class. Inter- and intra-observer reproducibility was evaluated by six observers of various backgrounds in a study of acute stroke patients. The software tool enabled a more detailed classification of the stroke lesion than would be possible with a region-of-interest approach. However, inter-observer coefficients of variation (CVs) were relatively high, reaching 70% in "possibly abnormal" tissue and around 15-20% in normal appearing tissues, while intra-observer CVs were no more than 13% in "possibly abnormal" tissue and generally less than 1% in normal-appearing tissues. The grid-overlay method overcomes some of the limitations of conventional Region Of Interest (ROI) approaches, providing a viable alternat...Continue Reading


Mar 1, 1994·Journal of Magnetic Resonance. Series B·P J BasserD LeBihan
Nov 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·L OstergaardB R Rosen
Dec 1, 1996·Radiology·C PierpaoliG Di Chiro
Aug 6, 1999·Stroke; a Journal of Cerebral Circulation·T Neumann-HaefelinH J Freund
Aug 23, 2001·Medical Image Analysis·M Jenkinson, S Smith
Oct 23, 2002·Human Brain Mapping·Stephen M Smith
Nov 19, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·S Muñoz ManiegaJ M Wardlaw
Nov 2, 2005·Journal of Magnetic Resonance Imaging : JMRI·Leif Østergaard
Sep 15, 2006·Annals of Neurology·Bartosz KaraszewskiMartin S Dennis
Aug 11, 2007·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Carly S RiversMartin S Dennis
Apr 7, 2009·NeuroImage·Renske de BoerWiro J Niessen
Aug 19, 2009·Journal of Neurology, Neurosurgery, and Psychiatry·Vera CvoroJoanna M Wardlaw
Oct 5, 2010·NMR in Biomedicine·Derek K Jones, Mara Cercignani

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Apr 11, 2013·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Bartosz KaraszewskiJoanna M Wardlaw

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