A health record integrated clinical decision support system to support prescriptions of pharmaceutical drugs in patients with reduced renal function: design, development and proof of concept

International Journal of Medical Informatics
Tero ShemeikkaSeher Korkmaz

Abstract

To develop and verify proof of concept for a clinical decision support system (CDSS) to support prescriptions of pharmaceutical drugs in patients with reduced renal function, integrated in an electronic health record system (EHR) used in both hospitals and primary care. A pilot study in one geriatric clinic, one internal medicine admission ward and two outpatient healthcare centers was evaluated with a questionnaire focusing on the usefulness of the CDSS. The usage of the system was followed in a log. The CDSS is considered to increase the attention on patients with impaired renal function, provides a better understanding of dosing and is time saving. The calculated glomerular filtration rate (eGFR) and the dosing recommendation classification were perceived useful while the recommendation texts and background had been used to a lesser extent. Few previous systems are used in primary care and cover this number of drugs. The global assessment of the CDSS scored high but some elements were used to a limited extent possibly due to accessibility or that texts were considered difficult to absorb. Choosing a formula for the calculation of eGFR in a CDSS may be problematic. A real-time CDSS to support kidney-related drug prescribing i...Continue Reading

References

Jan 1, 1976·Nephron·D W Cockcroft, M H Gault
Oct 30, 1998·JAMA : the Journal of the American Medical Association·D W BatesD L Seger
Oct 30, 1998·JAMA : the Journal of the American Medical Association·R A RaschkeC Susong
Aug 20, 2003·Journal of the American Medical Informatics Association : JAMIA·David W BatesBlackford Middleton
Mar 23, 2006·European Journal of Clinical Pharmacology·Marie EliassonLars L Gustafsson
Aug 2, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Hege Salvesen BlixAasmund Reikvam
Aug 16, 2006·Annals of Internal Medicine·Andrew S LeveyUNKNOWN Chronic Kidney Disease Epidemiology Collaboration
Apr 25, 2009·Journal of the American Medical Informatics Association : JAMIA·Terry S FieldJerry H Gurwitz
May 6, 2009·Annals of Internal Medicine·Andrew S LeveyUNKNOWN CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
May 19, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Lesley A StevensUNKNOWN Chronic Kidney Disease Epidemiology Collaboration
Oct 22, 2009·Clinical Pharmacology and Therapeutics·L A Stevens, A S Levey
Oct 22, 2009·Clinical Pharmacology and Therapeutics·W J SpruillH H Cobb
May 6, 2010·Journal of the American Medical Informatics Association : JAMIA·Gregory W RobertsRobert J Adams
May 6, 2011·Drugs & Aging·Andrea CorsonelloUNKNOWN Gruppo Italiano di Farmacovigilanza nell'Anziano (GIFA)
Sep 29, 2011·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Davy TawadrousAmit X Garg
Oct 4, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Keith McCulloughCorri Black
Oct 9, 2013·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Alexander A LeungDavid W Bates

❮ Previous
Next ❯

Citations

Jan 23, 2016·Clinical Kidney Journal·Björn RunessonJuan Jesús Carrero
Nov 26, 2015·International Journal of Medical Informatics·Rodrigo Alves TubeloFabrício Mezzomo Collares
May 26, 2017·International Journal of Clinical Practice·Wubshet Hailu TesfayeSyed Tabish R Zaidi
Dec 28, 2017·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Marion LepelleyJean-Luc Bosson
Aug 28, 2015·Journal of Medical Systems·José NevesHenrique Vicente
Jan 23, 2021·Pharmacy : Journal of Pharmacy, Education and Practice·Hanna JustadTora Hammar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.