A high blood level in the air trap reduces microemboli during hemodialysis

Artificial Organs
Ulf ForsbergBernd Stegmayr

Abstract

Previous studies have demonstrated the presence of air microemboli in the dialysis circuit and in the venous circulation of the patients during hemodialysis. In vitro studies indicate that a high blood level in the venous air trap reduces the extent of microbubble formation. The purpose of this study was to examine whether air microbubbles can be detected in the patient's access and if so, whether the degree of microbubble formation can be altered by changing the blood level in the venous air trap. This was a randomized, double-blinded, interventional study of 20 chronic hemodialysis patients. The patients were assigned to hemodialysis with either an elevated or a low blood level in the air trap. The investigator and the patient were blinded to the settings. The numbers of microbubbles were measured at the site of the arteriovenous (AV) access for 2 min with the aid of an ultrasonic Doppler device. The blood level in the air trap was then altered to the opposite setting and a new measurement was carried out after an equilibration period of 30 min. Median (range) for the number of microbubbles measured with the high air trap level and the low air trap level in AV access was 2.5 (0-80) compared with 17.5 (0-77), respectively (P =...Continue Reading

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Citations

Apr 30, 2015·Artificial Organs·David FulkerTracie Barber
Jul 6, 2013·Artificial Organs·Gholamreza KeshavarziJohn A Reizes
Mar 6, 2013·Artificial Organs·Paul S Malchesky
Aug 8, 2015·Clinical Kidney Journal·Stephan WagnerBernard Canaud
Apr 7, 2015·Journal of Biomechanics·Gholamreza KeshavarziTracie Barber
Oct 25, 2016·Seminars in Dialysis·Bernd G Stegmayr
Sep 1, 2016·Hemodialysis International·Bernd Stegmayr
Dec 20, 2020·The International Journal of Artificial Organs·Junko GotoBernd G Stegmayr
Jan 7, 2022·Hemodialysis International·Rupesh RainaAndrew Davenport

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