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A high-density admixture map for disease gene discovery in african americans

American Journal of Human Genetics

May 1, 2004

Michael W SmithDavid E. Reich

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Abstract

Admixture mapping (also known as "mapping by admixture linkage disequilibrium," or MALD) provides a way of localizing genes that cause disease, in admixed ethnic groups such as African Americans, with approximately 100 times fewer markers than are required for whole-genome haplotype sca...read more

Mentioned in this Paper

Alleles
Cell Differentiation Process
Chromosome Mapping
Chromosomes
Ethnic Group
Genetic Markers
Genetics, Population
Genome
Genome, Human
Genetic Linkage
152
2
Paper Details
References
  • References32
  • Citations278
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A high-density admixture map for disease gene discovery in african americans

American Journal of Human Genetics

May 1, 2004

Michael W SmithDavid E. Reich

PMID: 15088270

DOI: 10.1086/420856

Abstract

Admixture mapping (also known as "mapping by admixture linkage disequilibrium," or MALD) provides a way of localizing genes that cause disease, in admixed ethnic groups such as African Americans, with approximately 100 times fewer markers than are required for whole-genome haplotype sca...read more

Mentioned in this Paper

Alleles
Cell Differentiation Process
Chromosome Mapping
Chromosomes
Ethnic Group
152
2

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Paper Details
References
  • References32
  • Citations278
12345...

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