A high-efficiency photooxidation reactor for speciation of organic arsenicals by liquid chromatography-hydride generation-ICPMS

Analytical Chemistry
Tetsuya Nakazato, Hiroaki Tao

Abstract

A novel postcolumn photooxidation reactor with remarkably high efficiency was developed. It was installed into a system of liquid chromatography (LC) combined with inductively coupled plasma mass spectrometry (ICPMS) using a hydride generation (HG) technique to enable sensitive speciation of organic arsenicals. An LC eluent was passed into a reaction tube that runs through a low-pressure mercury lamp of a high-efficiency photooxidation (HEPO) reactor. It provided efficient irradiation with vacuum ultraviolet light at 185 nm, which induced oxidative decomposition of persistent organic arsenicals, for example, arsenobetaine, to the final product, arsenate, for an extremely short time, 3.5 s, without using any oxidizing agents. That arsenate was subsequently detectable by HG-ICPMS. In contrast, conventional photooxidation reactors require more than 100 s for completion, even when using a peroxodisulfate solution as an oxidizing agent. Because of the absence of broadening and dilution of the LC-separated peaks caused by mixing with the oxidant solution, the detection limits for 10 arsenic species including the persistent organic arsenicals by the proposed LC-HEPO-HG-ICPMS ranged from 2.3 to 18 ng of As/L, which were about one-tenth...Continue Reading

Citations

Aug 21, 2013·Archives of Environmental Contamination and Toxicology·Tomoko OguriTetsuya Nakazato
Sep 15, 2011·The Kaohsiung Journal of Medical Sciences·Keng-Chang HsuYeou-Lih Huang
Apr 16, 2009·Luminescence : the Journal of Biological and Chemical Luminescence·Junhai XueXinrong Zhang
Aug 11, 2012·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Toshihiro SuzukiHiroaki Tao
Feb 13, 2013·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Takayuki SatouHiroaki Tao
May 24, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Tomoko OguriTetsuya Nakazato
Mar 9, 2017·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·Tomoko OguriTetsuya Nakazato
Dec 1, 2006·Journal of Mass Spectrometry : JMS
Jul 3, 2010·Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan·Shinichi Miyashita, Toshikazu Kaise
Jul 15, 2015·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Hiroyuki YanagisawaOsamu Niwa
May 9, 2008·Analytical Chemistry·Nicolas H BingsJosé A C Broekaert
Nov 7, 2009·Analytical Chemistry·Mrinal K Sengupta, Purnendu K Dasgupta
Oct 24, 2007·Analytical Chemistry·Ademola D Idowu, Purnendu K Dasgupta

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