PMID: 119310Jan 1, 1979Paper

A high frequency of cytotoxic precursor cells for a syngeneic tumour

Scandinavian Journal of Immunology
H S Warren, K J Lafferty

Abstract

The average frequency of cytotoxic precursor cells in DBA/2 lymph node cell preparations reactive to the syngeneic tumour P815 has been determined as 1 in 2000. This frequency is similar to the precursor frequency for an allogeneic tumour EL-4. The normal lack of response of DBA/2 lymph node cells to the syngeneic tumour P815 in vitro cannot be attributed to a lack of cytotoxic precursor cells. We conclude that in this tumour-host system non-immunogenicity reflects a defect at the inductive step.

References

Apr 1, 1978·The Australian Journal of Experimental Biology and Medical Science·H S WarrenK J Lafferty
Feb 1, 1975·The Australian Journal of Experimental Biology and Medical Science·K J Lafferty, A J Cunningham
Oct 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·D W TalmageK J Lafferty
Apr 1, 1979·The Australian Journal of Experimental Biology and Medical Science·J A Woolnough, K J Lafferty
Jan 1, 1977·Immunological Reviews·K J Lafferty, J Woolnough

Citations

Mar 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·A F TilkinJ Urbain
Feb 21, 2016·The Science of the Total Environment·Martin A StapanianSteven E Monteith
Jan 1, 1980·Immunological Reviews·K J LaffertyS J Prowse

Related Concepts

Concanavalin A
Immunologic Tumoricidal Activities
Colony-Forming Units, Hematopoietic
Lymph Nodes
Lymphocyte Activation
Lymphoid Cells
Mice, Inbred DBA
Neoplasm Transplantation
Neoplasms, Experimental
Sarcoma, Jensen

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