Abstract
The aim of this work was to determine the effects in rats of ingesting 1 of 3 diets with normal or high protein concentrations and various carbohydrate:lipid ratios on weight gain, body composition, and the development and metabolism of white adipose tissue (WAT). For this purpose, male Wistar rats were fed for 20 or 42 d a high-carbohydrate, low-fat, normal-protein diet (76, 10, and 14% of energy as carbohydrate, lipid, and protein, respectively, carbohydrate:lipid ratio (C/L) = 7.6), a normal-carbohydrate, low-fat, high-protein diet (35, 10, and 55% of energy as carbohydrate, lipid, and protein respectively, C:L = 3.5), or a carbohydrate-free, high-fat, high-protein diet (45 and 55% of energy as fat and protein, respectively, C:L = 0). Growth, food intake, body composition, WAT cellularity, and several markers of lipogenesis including fatty acid synthase and lipoprotein lipase activities were measured in adipose tissue and liver. Lowering the C:L ratio reduced the development of WAT, weight gain, body fat mass, and adipocyte size, and in rats fed the carbohydrate-free diet (C:L = 0), the total number of adipocytes in subcutaneous WAT. These reductions in adipose tissue development with decreases in the C:L ratio of the diet s...Continue Reading
References
Jan 1, 1988·The Biochemical Journal·I DugailM Lavau
Oct 1, 1985·Analytical Biochemistry·P K SmithD C Klenk
Mar 1, 1973·The Biochemical Journal·A P Halestrap, R M Denton
Jul 1, 1971·The Journal of Nutrition·G L AlleeD H Baker
Apr 1, 1967·The American Journal of Physiology·R B Goldrick
Nov 1, 1983·The Journal of Nutrition·R W Swick, C L Gribskov
Mar 1, 1984·Metabolism: Clinical and Experimental·H SchmidR H Migliorini
Dec 8, 1995·The Journal of Biological Chemistry·S M Dudek, C F Semenkovich
Jan 1, 1997·Annual Review of Nutrition·H C TowleH M Shih
Aug 26, 1998·Annual Review of Nutrition·H S Sul, D Wang
Feb 24, 2001·The Journal of Nutrition·C JeanD Tomé
Jun 14, 2002·Physiology & Behavior·Ahmed BensaïdGilles Fromentin
May 25, 2004·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Magali LacroixJean-François Huneau
Oct 7, 2004·The Journal of Nutrition·Agnes Marsset-BaglieriPatrick C Even
Citations
Jul 5, 2007·Clinical Science·Natalia SinitskayaEtienne Challet
Oct 2, 2008·Current Opinion in Clinical Nutrition and Metabolic Care·Isabelle A Leclercq, Yves Horsmans
Sep 10, 2009·American Journal of Physiology. Endocrinology and Metabolism·Nattida ChotechuangDaniel Tomé
Jun 19, 2010·Experimental Biology and Medicine·Ren-Ying XuWei Cai
Apr 15, 2010·Annals of the New York Academy of Sciences·Lise Madsen, Karsten Kristiansen
Oct 28, 2010·Nutrition Research Reviews·Niloofar Hariri, Louise Thibault
Sep 8, 2011·Aging Cell·Ligen LinYuxiang Sun
Mar 24, 2012·Animal : an International Journal of Animal Bioscience·M KuciaC C Metges
Oct 5, 2012·The American Journal of Clinical Nutrition·Fanny TheytazLuc Tappy
Apr 14, 2015·Preventive Nutrition and Food Science·Ryota HosomiKenji Fukunaga
Mar 28, 2017·Obesity Surgery·Joana RossellJuan Antonio Baena-Fustegueras
Apr 5, 2017·Frontiers in Nutrition·Tristan Chalvon-DemersayAnne Blais
Sep 29, 2017·Nutrients·Giuseppe Della PepaAngela Albarosa Rivellese
Nov 7, 2017·International Journal of Food Sciences and Nutrition·Gianluca GiubertiFilippo Rossi
Jan 12, 2019·Frontiers in Physiology·Lise MadsenKarsten Kristiansen
Jun 10, 2020·The British Journal of Nutrition·Neda HaghighatAlexei Wong
Feb 18, 2011·PloS One·Magdalena StepienDalila Azzout-Marniche
Dec 21, 2010·European Journal of Nutrition·Anne NoatschSusanne Klaus
Mar 5, 2015·PloS One·Morten Rahr ClausenHanne C Bertram
Oct 1, 2014·Food & Function·Rubén Díaz-RúaPaula Oliver
Mar 31, 2016·American Journal of Physiology. Endocrinology and Metabolism·Pia KiilerichKarsten Kristiansen
Jul 8, 2016·Adipocyte·Ulrike LiisbergLise Madsen
Mar 20, 2018·Nature Communications·Helen J DranseTony K T Lam
Mar 17, 2020·BMC Pediatrics·Mi Jin Kim, Kyung Jae Lee
Jul 31, 2009·The American Journal of Clinical Nutrition·Daniel ToméGilles Fromentin
Mar 26, 2010·The Journal of Nutrition·Magdalena StepienPatrick Even
Nov 3, 2010·Stress : the International Journal on the Biology of Stress·A Nadal-CasellasI Llad
Oct 5, 2010·Amino Acids·Claire FromentinClaire Gaudichon
Nov 17, 2007·The British Journal of Nutrition·Lisa PichonGilles Fromentin
Dec 10, 2008·The Journal of Physiology·Alannah D MaurerRaylene A Reimer
Dec 6, 2008·Current Opinion in Clinical Nutrition and Metabolic Care·Mylène PotierDaniel Tomé
Oct 23, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Weiwei DaiSandrine Skiba-Cassy
Aug 20, 2015·The British Journal of Nutrition·Catherine ChaumontetDaniel Tomé
Mar 31, 2016·International Journal of Molecular Sciences·David HoughtonMichael Trenell
May 28, 2019·Nutrients·Lene Secher MyrmelLise Madsen
Jan 30, 2020·Nutrients·Caroline Desclée de MaredsousAnne-Marie Davila
Aug 23, 2020·Nutrients·Sally A V DraycottSimon Langley-Evans
Dec 13, 2006·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Dalila Azzout-MarnicheDaniel Tomé
Nov 18, 2008·NMR in Biomedicine·T C DelgadoJ G Jones
Oct 12, 2010·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Laure ChevalierClaire Gaudichon
Apr 20, 2007·The British Journal of Nutrition·Aml ErhumaAndrew J Bennett
Apr 9, 2013·The British Journal of Nutrition·Megan C Hallam, Raylene A Reimer
Apr 1, 2016·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Dalila Azzout-MarnichePatrick C Even
Sep 2, 2016·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Magdalena StepienClaire Gaudichon
Jan 10, 2018·Frontiers in Physiology·Lise MadsenKarsten Kristiansen
Dec 20, 2019·Journal of Animal Science·Peter K AjuoguNeil A Smart
Feb 13, 2014·PloS One·Liam McAllanKanishka N Nilaweera
Dec 3, 2010·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Ousseynou SarrIsabelle Louveau
Apr 24, 2015·PloS One·Ruth ChanHenry Lik-Yuen Chan
Nov 25, 2020·International Journal of Molecular Sciences·Rosa LombardiAnna Ludovica Fracanzani