A high-resolution radiation hybrid map of porcine chromosome 6

Animal Genetics
Honghe CaoA M Verrinder Gibbins

Abstract

A high-resolution comprehensive map was constructed for porcine chromosome (SSC) 6, where quantitative trait loci (QTL) for reproduction and meat quality traits have been reported to exist. A radiation hybrid (RH) map containing 105 gene-based markers and 15 microsatellite markers was constructed for this chromosome using a 3000-rad porcine/hamster RH panel. In total, 40 genes from human chromosome (HSA) 1p36.3-p22, 29 from HSA16q12-q24, 17 from HSA18p11.3-q12 and 19 from HSA19q13.1-q13.4 were assigned to SSC6. All primers for these gene markers were designed based on porcine gene or EST sequences, and the orthologous status of the gene markers was confirmed by direct sequencing of PCR products amplified from separate Meishan and Large White genomic DNA pools. The RH map spans SSC6 and consists of six linkage groups created by using a LOD score threshold of 4. The boundaries of the conserved segments between SSC6 and HSA1, 16, 18 and 19 were defined more precisely than previously reported. This represents the most comprehensive RH map of SSC6 reported to date. Polymorphisms were detected for 38 of 105 gene-based markers placed on the RH map and these are being exploited in ongoing chromosome wide scans for QTL and eventual fine...Continue Reading

References

May 26, 1999·Mammalian Genome : Official Journal of the International Mammalian Genome Society·P J WilkieL B Schook
Aug 3, 1999·Mammalian Genome : Official Journal of the International Mammalian Genome Society·R J HawkenL J Alexander
Apr 8, 2000·Mammalian Genome : Official Journal of the International Mammalian Genome Society·P PintonM Yerle
Apr 8, 2000·Mammalian Genome : Official Journal of the International Mammalian Genome Society·C OviloJ L Noruera
May 3, 2000·Mammalian Genome : Official Journal of the International Mammalian Genome Society·M R AmaranteJ E Womack
Dec 29, 2000·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Y Lahbib-MansaisJ Gellin
Mar 27, 2001·Journal of Animal Science·J P CassadyK M Gilson
Apr 20, 2001·Mammalian Genome : Official Journal of the International Mammalian Genome Society·E GrindflekS Lien
Jun 23, 2001·Mammalian Genome : Official Journal of the International Mammalian Genome Society·A B KarnuahT Mitsuhashi
Aug 15, 2002·Genome Génome / Conseil National De Recherches Canada·Zhihua JiangAnn M Verrinder Gibbins
Nov 7, 2002·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Anette RinkCraig W Beattie

❮ Previous
Next ❯

Citations

May 12, 2009·BMC Genomics·Jian-Gang MaWan-Sheng Liu
Oct 10, 2009·The Journal of Reproduction and Development·Laura Francesca PisaniPaola Mariani
Mar 6, 2013·The Journal of Immunology : Official Journal of the American Association of Immunologists·Qunwei WangAndrew M Jackson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Mammalian Genome : Official Journal of the International Mammalian Genome Society
A P RattinkB Harlizius
Mammalian Genome : Official Journal of the International Mammalian Genome Society
R HawkenL J Alexander
Mammalian Genome : Official Journal of the International Mammalian Genome Society
Olivier DemeureDenis Milan
© 2021 Meta ULC. All rights reserved