PMID: 7541968Jun 1, 1995Paper

A high risk of hepatitis C infection among Egyptian blood donors: the role of parenteral drug abuse

The American Journal of Tropical Medicine and Hygiene
S BassilyR G Hibbs

Abstract

To determine the prevalence and risk factors of hepatitis C virus (HCV) infection among Egyptian blood donors, 188 consecutive adult blood donors from four hospitals and one temporary donor center located in Cairo, Egypt were evaluated. Sera were tested for HCV antibodies (anti-HCV) using second-generation enzyme-linked immunosorbent assay (ELISA) test kits. Sera that were repeatedly reactive by ELISA were further verified by a second-generation recombinant immunoblot assay (RIBA). Antibodies to HCV were detected by RIBA in 26.6% of the blood donors, which is higher than the 10-19% prevalence of antibody found in other studies of Egyptian blood donors. A history of selling blood (odds ratio [OR] = 12.1) and the use of illicit parenteral drugs (OR = 2.5) were significantly associated with anti-HCV seropositivity after controlling for age and gender. These data indicate that the use of illicit drugs may be one reason for high levels of reported HCV infection among Egyptian blood donors. These findings also indicate that Egyptian blood donors should be screened for anti-HCV and individuals who have a history of drug abuse should be deferred from donating blood.

Citations

Jan 6, 2006·European Journal of Gastroenterology & Hepatology·Geert RobaeysUNKNOWN Benelux Study Group
Nov 1, 1996·Transactions of the Royal Society of Tropical Medicine and Hygiene·A L CorwinK C Hyams
Dec 18, 2009·Liver International : Official Journal of the International Association for the Study of the Liver·Nabil AntakiPatrick Marcellin
Aug 11, 2010·Proceedings of the National Academy of Sciences of the United States of America·F DeWolfe Miller, Laith J Abu-Raddad
Jun 27, 2013·BMC Infectious Diseases·Yousra A MohamoudLaith J Abu-Raddad
Aug 31, 2002·Journal of Gastroenterology and Hepatology·Seyed Moayed AlavianSadegh Masarrat
Dec 22, 2006·Vox Sanguinis·L H ToblerM P Busch
May 1, 1997·Transactions of the Royal Society of Tropical Medicine and Hygiene·R R ArthurI Z Imam
Apr 9, 1999·Sexually Transmitted Infections·G Rooney, R J Gilson

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