A Homeopathic Combination Preparation in the Treatment of Feverish Upper Respiratory Tract Infections: An International Randomized Controlled Trial

Forschende Komplementärmedizin = Research in Complementary Medicine
Manuela Thinesse-MallwitzPetra Klement

Abstract

Upper respiratory tract infections (URTI) are very common and associated with considerable healthcare costs. We evaluated the clinical benefit of a homeopathic add-on therapy. In this randomized controlled multinational clinical trial, patients (age range 1-65 years) with feverish URTI received either on-demand symptomatic standard treatment (ST group: paracetamol, ambroxol, and/or oxymetazoline), or homeopathic medication (IFC group: Influcid®) for 7 days plus the same on-demand standard treatment. URTI symptoms were assessed using the Wisconsin Upper Respiratory Symptom Survey-21. Response at day 4, defined as absence of fever and absence or very mild degree of URTI symptoms, was the primary outcome measure. 523 patients (265 IFC group, 258 ST group) were randomized in 12 Ukrainian and 10 German centers. The responder rate on day 4 was 15.4% in the IFC group and 6.7% in the ST group (x0394;IFC-ST = 8.7%, 95% confidence interval 2.9-14.5%). The IFC group used less symptomatic medication, and symptoms were alleviated 1-2 days earlier. 3 and 8 adverse events (AEs) in the IFC and ST group, respectively, were assessed as possibly treatment-related; 2 out of the 3 AEs in the IFC group were possibly related to symptomatic therapy, 1...Continue Reading

Citations

Mar 1, 2018·Complementary Medicine Research·Harald Walach
Apr 6, 2018·MMW Fortschritte der Medizin·André-Michael Beer
Apr 10, 2018·The Cochrane Database of Systematic Reviews·Kate HawkeDavid King
Oct 6, 2020·Frontiers in Public Health·Mohammed Dauda GoniBabagana Mohammed Adam
Jun 23, 2021·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Laurel TeohAnne B Chang

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