A huffing manoeuvre, immediately before induction of anaesthesia, prevents fentanyl-induced coughing: a prospective, randomized, and controlled study

British Journal of Anaesthesia
Sushil AmbeshUttam Singh

Abstract

Preinduction i.v. fentanyl bolus is associated with coughing in 28-65% of patients. Fentanyl-induced coughing (FIC) is not always benign and can be remarkably troublesome at the most critical moment of induction of anaesthesia when airway reflex is lost. We postulated that the huffing manoeuvre, a forced expiration against open glottis, just before i.v. fentanyl, may suppress this undesirable spasmodic cough. Three hundred patients of ASA I and II, aged 18-60 yr, undergoing elective surgical procedures were randomly allocated into two groups consisting of 150 patients. Both groups received i.v. fentanyl (2.5 microg kg(-1)). Group 1 patients breathed normally whereas Group 2 patients were asked to perform huffing manoeuvre just before the fentanyl injection. The incidence of cough was recorded for 1 min before the induction of anaesthesia, and graded as mild (1-2 cough), moderate (3-5 cough), and severe (>5 cough). The incidence of FIC was analysed with Fisher's exact test and severity was analysed with the Mann-Whitney U-test. A P-value of <0.05 was considered significant. The incidence of cough was 32% in the control group and 4% in the huffing manoeuvre group (P<0.00). In the control group, 12% of FIC cases were moderate to s...Continue Reading

References

Aug 1, 1978·Anesthesiology·I YasudaM Satoh
Sep 1, 1978·Respiration Physiology·S LahiriA P Fishman
Apr 1, 1991·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·W T PhuaW A Tweed
Aug 1, 1969·The Journal of Physiology·A S Paintal
Jul 1, 1982·Respiration Physiology·F B Sant'Ambrogio, G Sant'Ambrogio
Dec 1, 1996·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·P W LuiY C Chu
Mar 7, 2003·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Anil AgarwalUttam Singh
Aug 18, 2004·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Chin-Shuang LinMartin S Mok
Feb 3, 2005·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Chandra Kant PandeyPrabhat Kumar Singh
Feb 3, 2005·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Christoph J Schlimp, Franz J Wiedermann
Aug 24, 2005·Anesthesia and Analgesia·Jui-An LinChih-Shung Wong
Aug 30, 2005·Journal of Pharmacological Sciences·Motomu Tanaka, Kei Maruyama
Jun 21, 2007·Acta Anaesthesiologica Scandinavica·H-C HorngC-T Wu

❮ Previous
Next ❯

Citations

Nov 14, 2013·Anesthesiology and Pain Medicine·Abbas SedighinejadAhmadreza Mirblook
Jun 5, 2010·Anaesthesia·D H Elcock
Dec 25, 2015·Journal of Anaesthesiology, Clinical Pharmacology·Abolfazl FirouzianAlieh Zamani Kiasari
Oct 1, 2016·Journal of Clinical Anesthesia·Li ShuyingLuo Dong
Jul 9, 2011·Korean journal of anesthesiology·Jong In Han
Oct 1, 2019·The Journal of Craniofacial Surgery·Fang Yin, Tiejun Zhang
Dec 17, 2020·Frontiers in Pharmacology·Rong ChenQing-Tao Meng
Jan 29, 2022·European Journal of Clinical Pharmacology·Nuanwan PhuvachoterojanaphokinSithapan Munjupong

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved