A huge benign fibrous histiocytoma arising from the renal capsule: report of a case

BMC Nephrology
Chao SunXueting Sun

Abstract

Neoplasms originating in the renal capsule are very rare. Benign fibrous histiocytoma(BFH) most commonly occurs in the dermis and subcutis, few cases of this tumor appear in the renal capsule. In particular, BFH larger than 20 cm are scarce. Here we report a rare huge one measuring 23 × 13 × 7 cm. We report a 64-year-old man who presented with a few-months history of dull pain in the right groin. The tumor had its point of origin in the renal capsule which is a rare condition. Histologically, the tumor was composed of intersecting fascicles of fibroblastic cells forming a "storiform" pattern. Immunohistochemical studies were also performed, ultimately leading to the diagnosis of BFH. The patient was treated with radical nephrectomy. No recurrence was detected 4 months after surgery. BFH arising from the renal capsule was very rare. In particular, the case of more than twenty centimeters is extremely rare. The clinical presentation of renal BFH might be only a mass. However, differential diagnosis from renal cell carcinoma proved to be impossible before surgical intervention. It is difficult to diagnose only by means of histopathology, but the immunohistochemical method can provide a clear and definite diagnosis.

References

Dec 1, 1989·The Journal of Urology·N SakakibaraT Koyanagi
Apr 1, 2000·Urologia Internationalis·A PtochosT Kehagia-Koutoufari
Feb 19, 2002·Scandinavian Journal of Urology and Nephrology·M TarjánZ Szabó
Oct 14, 2005·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Kazuhiro KitajimaKazuro Sugimura
Aug 2, 2007·Ophthalmic Plastic and Reconstructive Surgery·Christopher S BoehlkeVictor M Elner
Apr 11, 2012·Archives of Orthopaedic and Trauma Surgery·Kontogeorgakos A VasileiosBrian E Brigman
May 13, 2014·Indian Journal of Ophthalmology·Pushpa VarmaRaju Manglawat
Sep 1, 2013·Turkish Journal of Urology·Çağatay GöğüşMut Şafak
Apr 8, 2016·The Journal of Craniofacial Surgery·Zhen LiQi Pang
Sep 25, 2017·Indian Journal of Pathology & Microbiology·Shilpa BairwaAjay Yadav

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Methods Mentioned

BETA
electron microscopy

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