PMID: 1196854Dec 1, 1975Paper

A hypophysis-abscess-syndrome in cattle III. Pathogenesis (author's transl)

Nordisk Veterinaermedicin
G Espersen, T Moller

Abstract

The pathogenesis of a hypophysis-absces-syndrome in cattle is discussed on the basis of clinical (Espersen 1975) and pathomorphological (Møller and Espersen 1975) investigations. It is concluded that several pathogenetic mechanisms are possible. A remarkable high incidence of the syndrome in recently ringed bulls point to the possibility of a porogenous spread from the nasal septum to the meninges and brain. The often occurring traumatic horn lesions with subsequent sinusitis suggest a porogenous spread from the sinus to the meninges and brain. On the other hand, traumatic horn lesions seem more often to occur as a secondary event and caused by automutilation, as a consequence of the pain, which is thought to accompany a primary meningo-encephalitis. The localization of the abscess in the hypophysis seems, in the majority of cases, to be a result of a primary, purulent meningo-encephalitis, with accumulation of pus from the brain ventricles to the infundibulum and pituitary cleft, due to gravitational forces. In some cases possibly as an extension from a basal meningitis. A direct, hematogenous metastasis to the frontal lobe of the pituitary is a further possibility. Ascending infection through a persistent cranio-pharyngeal du...Continue Reading

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