DOI: https://doi.org/10.51189/rema/793Mar 23, 2021Proceedings Paper

A IMPORTÂNCIA DOS BIOMARCADORES NO MANEJO DA AIDS

Leonardo de Oliveira Assis, Danielli Carolina Brito Souza

Abstract

Introdução: Os biomarcadores são extremamente importantes devido à alta sensibilidade e especificidade em determinar alterações fisiopatológicas em sistemas biológicos humanos. Uma série de estudos com proteínas virais vêm sendo conduzidos de forma a aplicar os já tradicionais bem como os mais recentes marcadores descobertos a fim de possibilitar um manejo mais humanizado de pessoas vivendo com HIV. Objetivo: Desenvolver uma análise crítica entre os pontos de vista dos autores sobre a importância dos biomarcadores no manejo da síndrome da imunodeficiência humana adquirida. Material e métodos: A metodologia selecionada para o cumprimento do objetivo foi a revisão sistemática da literatura. Os artigos foram selecionados de 2016 a 2021 por meio de busca on-line nas bases de dados PubMed, Cochrane e Lilacs, partindo de consulta à Biblioteca Virtual em Saúde. Os termos “mesh” utilizados para pesquisa dos estudos foram: biomarcadores, HIV, AIDS e tratamento. Resultados: A partir da busca realizada nas bases de dados foram selecionadas 11 publicações para compor o estudo. É importante citar que o DNA total do HIV-1, mensurado por PCR em tempo real, trata-se do marcador mais empregado além de ser capaz de dimensionar todas as formas de...Continue Reading

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