A kinetic description of how interfaces accelerate reactions in micro-compartments.

Chemical Science
Kevin WilsonMichael Jacobs

Abstract

A kinetic expression is derived to explain how interfaces alter bulk chemical equilibria and accelerate reactions in micro-compartments. This description, aided by the development of a stochastic model, quantitatively predicts previous experimental observations of accelerated imine synthesis in micron-sized emulsions. The expression accounts for how reactant concentration and compartment size together lead to accelerated reaction rates under micro-confinement. These rates do not depend solely on concentration, but rather the fraction of total molecules in the compartment that are at the interface. Although there are ∼107 to 1013 solute molecules in a typical micro-compartment, a kind of "stochasticity" appears when compartment size and reagent concentration yield nearly equal numbers of bulk and interfacial molecules. Although this is distinct from the stochasticity produced by nano-confinement, these results show how interfaces can govern chemical transformations in larger atmospheric, geologic and biological compartments.

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Citations

Jun 5, 2021·The Journal of Physical Chemistry Letters·Chaya WeeraratnaMusahid Ahmed
Mar 20, 2021·The Journal of Physical Chemistry. B·Andrew P CarpenterGeraldine L Richmond
Apr 17, 2021·Environmental Science & Technology·Ruifeng ZhangChak K Chan
May 13, 2021·The Journal of Physical Chemistry. a·Alexandra M DealVeronica Vaida
Jul 30, 2021·Chemical Reviews·Cristina Lento, Derek J Wilson
Aug 10, 2021·The Journal of Physical Chemistry. B·Musahid AhmedKevin R Wilson
Oct 1, 2021·Electrophoresis·Husam KafeenahShu-Hui Chen
Dec 3, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Michael I JacobsCharles M Schroeder

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Software Mentioned

Mathematica
Kinetiscope©

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