PMID: 4899880Jul 1, 1969Paper

A lipid requirement for induction of lactose transport in Escherichia coli

Proceedings of the National Academy of Sciences of the United States of America
C F Fox

Abstract

The rate of derepressed synthesis of a membrane protein required for lactose transport (M protein) by Escherichia coli is increased in response to increased gene dosage to the same extent as the rates of synthesis of beta-galactosidase and galactoside acetylase. However, elevated gene dosage does not increase beta-galactoside transport to the same extent that it increases synthesis of M protein and of the soluble proteins of the lac operon. Though the factor or factors other than M protein which limit induction of the transport system at high levels of lac operon expression have not been identified, studies with Escherichia coli mutants blocked in the synthesis of unsaturated fatty acids indicate that unsaturated fatty acids must be supplied during the course of induction of the lac operon to permit synthesis of a functional lactose transport system, but not of beta-galactosidase or galactoside acetylase.

References

Oct 11, 1967·Biochemical and Biophysical Research Communications·P Overath, E M Raufuss
Oct 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·D F Silbert, P R Vagelos
Mar 2, 1968·Nature·K IppenJ Beckwith
Jun 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·J R CarterE P Kennedy
Sep 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·C F Fox, E P Kennedy
Jun 1, 1961·Journal of Molecular Biology·F JACOB, J MONOD

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Citations

Jan 1, 1983·Molecular & General Genetics : MGG·H L MobleyB P Rosen
Dec 1, 1978·Archives of Biochemistry and Biophysics·M SinghR Prasad
Dec 22, 1999·Biochimica Et Biophysica Acta·W E Lands
Oct 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·C F FoxG Wilson
Feb 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·L Mindich
Apr 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·H F Kung, U Henning
Aug 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·A R Robbins, B Rotman
Feb 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·M GlaserP R Vagelos
Dec 31, 1973·Annals of the New York Academy of Sciences·J Urbina, J S Waugh
Apr 3, 1973·Biochimica Et Biophysica Acta·R Coleman
Feb 14, 1972·Biochimica Et Biophysica Acta·J E Cronan, P R Vagelos
Aug 25, 1977·Journal of Molecular Biology·V A Fried
May 22, 1970·Biochemical and Biophysical Research Communications·C HennautM Grenson
Feb 12, 1981·Biochemical and Biophysical Research Communications·K ChandraboseR Pottathil
Jun 4, 1971·Biochemical and Biophysical Research Communications·G A Scarborough
Jan 23, 1973·Biochemical and Biophysical Research Communications·J T HoldenC N Kenyon
Dec 17, 1971·Biochemical and Biophysical Research Communications·K Izui
Mar 9, 1971·Biochimica Et Biophysica Acta·J T WongP M Bronskill
Feb 20, 1970·Biochemical and Biophysical Research Communications·G WilsonC F Fox
May 30, 1978·Biochemical and Biophysical Research Communications·I R Beacham, S Jones
Apr 17, 2018·International Journal of Molecular Sciences·Bruno André
Jan 1, 1973·Journal of Supramolecular Structure·N A Machtiger, C F Fox
Dec 29, 1971·Nature: New Biology·P OverathI Lamnek-Hirsch
Jul 1, 1971·Journal of Bacteriology·J P Ballesta, M Schaechter
Sep 1, 1971·Journal of Bacteriology· von Meyenburg Kaspar
Jun 1, 1972·Journal of Bacteriology·B P Rosen, S L Hackette
Aug 1, 1970·Journal of Bacteriology·P C WuA Newton

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