A literature review of 2019 novel coronavirus (SARS-CoV2) infection in neonates and children.

Pediatric Research
Matteo Di NardoVito Marco Ranieri

Abstract

At the time of writing, there are already millions of documented infections worldwide by the novel coronavirus 2019 (2019-nCoV or severe acute respiratory syndrome coronavirus 2 (SARS-CoV2)), with hundreds of thousands of deaths. The great majority of fatal events have been recorded in adults older than 70 years; of them, a large proportion had comorbidities. Since data regarding the epidemiologic and clinical characteristics in neonates and children developing coronavirus disease 2019 (COVID-19) are scarce and originate mainly from one country (China), we reviewed all the current literature from 1 December 2019 to 7 May 2020 to provide useful information about SARS-CoV2 viral biology, epidemiology, diagnosis, clinical features, treatment, prevention, and hospital organization for clinicians dealing with this selected population. IMPACT: Children usually develop a mild form of COVID-19, rarely requiring high-intensity medical treatment in pediatric intensive care unit. Vertical transmission is unlikely, but not completely excluded. Children with confirmed or suspected COVID-19 must be isolated and healthcare workers should wear appropriate protective equipment. Some clinical features (higher incidence of fever, vomiting and dia...Continue Reading

References

Sep 25, 2017·Intensive Care Medicine·Martin C J KneyberUNKNOWN section Respiratory Failure of the European Society for Paediatric and Neonatal Intensive Care
Jan 25, 2020·The New England Journal of Medicine·Na ZhuUNKNOWN China Novel Coronavirus Investigating and Research Team
Feb 7, 2020·World Journal of Pediatrics : WJP·Kun-Ling Shen, Yong-Hong Yang
Feb 7, 2020·World Journal of Pediatrics : WJP·Zhi-Min ChenYuan-Yuan Zhang
Feb 8, 2020·Clinical Chemistry·Daniel K W ChuLeo L M Poon
Feb 8, 2020·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Scott L WeissPierre Tissieres
Feb 9, 2020·World Journal of Pediatrics : WJP·Kunling ShenUNKNOWN Global Pediatric Pulmonology Alliance
Feb 12, 2020·The Lancet Child & Adolescent Health·Jianhui WangUNKNOWN National Clinical Research Center for Child Health and Disorders and Pediatric Committee of Medical Association of Chinese P
Feb 15, 2020·JAMA : the Journal of the American Medical Association·Min WeiZhi-Jiang Zhang
Feb 20, 2020·Infection·Zhangkai J Cheng, Jing Shan
Feb 23, 2020·The Lancet. Gastroenterology & Hepatology·Charleen YeoDanson Yeo
Feb 29, 2020·The New England Journal of Medicine·Wei-Jie GuanUNKNOWN China Medical Treatment Expert Group for Covid-19
Mar 1, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jiehao CaiMei Zeng
Mar 3, 2020·Journal of Medical Virology·Qi Lu, Yuan Shi
Mar 7, 2020·Archives of Disease in Childhood. Fetal and Neonatal Edition·Fang LiYuan Shi
Mar 7, 2020·Emerging Infectious Diseases·Yang LiJifang Sheng
Mar 7, 2020·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Qing CaoCheng-Hsun Chiu
Mar 7, 2020·The Journal of Infection·Pu YangDongchi Zhao
Mar 10, 2020·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Ping-Ing LeePo-Ren Hsueh
Mar 11, 2020·The Lancet Child & Adolescent Health·Daniele De Luca
Mar 11, 2020·Translational Pediatrics·Huaping ZhuWenhao Zhou
Mar 11, 2020·Annals of Translational Medicine·Laishuan WangUNKNOWN Working Committee on Perinatal and Neonatal Management for the Prevention and Control of the 2019 Novel Coronavirus Infectio
Mar 13, 2020·Pediatric Radiology·Wei LiShaolin Li
Mar 13, 2020·The New England Journal of Medicine·Weiyong LiuYingle Liu
Mar 14, 2020·World Journal of Pediatrics : WJP·Yan Wang, Li-Qin Zhu
Mar 14, 2020·Indian Journal of Pediatrics·Tanu Singhal
Mar 17, 2020·Clinical Chemistry and Laboratory Medicine : CCLM·Brandon Michael HenryMario Plebani
Mar 17, 2020·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Chih-Cheng LaiPo-Ren Hsueh
Mar 17, 2020·Journal of Korean Medical Science·UNKNOWN Korean Society of Infectious DiseasesUNKNOWN Korea Centers for Disease Control and Prevention
Mar 18, 2020·Pediatrics·Yuanyuan DongShilu Tong
Mar 18, 2020·JAMA : the Journal of the American Medical Association·Edward Livingston, Karen Bucher
Mar 18, 2020·The New England Journal of Medicine·Neeltje van DoremalenVincent J Munster
Mar 19, 2020·The New England Journal of Medicine·Xiaoxia LuUNKNOWN Chinese Pediatric Novel Coronavirus Study Team
Mar 21, 2020·Lancet·Puja MehtaUNKNOWN HLH Across Speciality Collaboration, UK
Mar 21, 2020·Lancet·Juliet BedfordUNKNOWN WHO Strategic and Technical Advisory Group for Infectious Hazards

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Citations

Jul 18, 2020·Pediatric Research·Matteo Di NardoVito Marco Ranieri
Oct 4, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Matteo Di NardoUNKNOWN EuroELSO Neonatal & Pediatric Working Group & collaborators on COVID-19
Dec 3, 2020·Revista paulista de pediatria : orgão oficial da Sociedade de Pediatria de São Paulo·Anna Clara RabhaGustavo Falbo Wandalsen
Mar 7, 2021·The Lancet Child & Adolescent Health·Dylan GraetzDaniel C Moreira
May 9, 2021·World Journal of Pediatrics : WJP·Alireza GhodsiSara Ghahremani
Jun 22, 2021·Frontiers in Pediatrics·Samira Shizuko Parreão OiGyl Eanes Barros Silva
Nov 6, 2021·Italian Journal of Pediatrics·Claudio Barbiellini AmideiLiviana Da Dalt

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