A longitudinal examination of parent-reported emotional-behavioral functioning of children with mild to moderate chronic kidney disease.

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
Rebecca J JohnsonS R Hooper

Abstract

Children with mild to moderate chronic kidney disease (CKD) are at increased risk for deficits in neurocognition. Less is known about how CKD affects emotional-behavioral functioning in this population. Parent ratings of emotional-behavioral functioning at baseline and over time were examined for 845 children with mild to moderate CKD using the Behavior Assessment System for Children, Second Edition Parent Rating Scales (BASC-2 PRS). Associations with demographic and disease-related predictors were also examined. Children with mild to moderate CKD had parent-reported emotional-behavioral functioning largely within normal limits, at baseline and over time. The proportion with T-scores at least 1 SD above the mean was 24% for Internalizing Problems and 28% for Attention Problems. A greater proportion of participants scored lower than expected (worse) on scales measuring adaptive skills (25%). Persistent hypertension predicted attention problems (β = 1.59, 95% CI = 0.24 to 2.94, p < 0.02) and suggested worse behavioral symptoms (β = 1.36, 95% CI = - 0.01 to 2.73, p = 0.05). Participants with proteinuria at baseline, but not at follow-up, had fewer attention problems than participants whose proteinuria had not resolved (β = - 3.48,...Continue Reading

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Citations

Apr 26, 2020·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Joann CarlsonSusan Furth
Apr 24, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Anne E DawsonCamille S Wilson
Jul 19, 2021·Pediatric Research·Ellen van der PlasLyndsay A Harshman

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