A longitudinal study of the effect of ocular biometrics measures on myopia onset.

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Zhengyang TaoMinjuan Zhu

Abstract

To investigate the relationship between ocular biometrics (OB) and myopia onset. OB data from students in 4 grades (aged from 6 to 14 years) in China were collected in a 1.5-year longitudinal study. Refractive error was assessed with cycloplegic autorefraction. At baseline, 934 (56.33%) of the subjects (right eye) had myopia. The mean spherical equivalent (SE) and axial length to corneal radius (AL/CR) were - 2.14 ± 1.49 and 3.14 ± 0.11, respectively, in the subjects with myopia and - 0.09 ± 0.21 and 2.98 ± 0.07, respectively, in the subjects without myopia. The correlation between the SE and AL/CR was r = - 0.823 (P < 0.001). The slopes of the SE changing with the AL/CR (and R-squares) were - 0.28 to - 1.80 (0.01-0.14) in the no myopia group, - 3.40 to - 6.20 (0.20-0.48) in the low myopia group, and - 3.37 to - 11.34 (0.16-0.74) in the moderate and high myopia groups. The baseline AL/CR values in grades 1, 3, and 5 were higher in those who developed myopia within 1.5 years. The odds ratio of the AL/CR to myopia onset in 1.5 years was 1.096 (95% confidence interval (CI): 1.060-1.135). Of the five indicators, the AL/CR showed the best correlation with the SE. The adjoint and linear relationship between the AL/CR and the SE tende...Continue Reading

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Citations

Mar 28, 2021·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Franziska G RauscherRalph Michael

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