PMID: 11605490Oct 19, 2001Paper

A lumped parameter model of the peripheral extra-corporeal circulation

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
X WangP Zheng

Abstract

A three-element model of lumped parameter in peripheral extra-corporeal circulation of an animal has been proposed and set up according to the fluid network theory. GEAR method, appropriate for the computation of the rigid problems, was used to solve the ordinary differential equations, so that a good convergence of the solution to the equations has been achieved. Physiological data of a 20 kg dog, obtained from our animal experiments were used to calculate the pressure and flow rate of important organs. The results of the mathematical model and animal tests showed that the peripheral extra-corporeal circulation could supply enough blood to the important organs, e.g. heart and brain, when the natural heart beating stopped. The results from both theoretical and experiments are critical to the cardiopulmonary cerebral resuscitation for the animals as well as for human beings.

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