A Machine Learning Approach to Understanding Patterns of Engagement With Internet-Delivered Mental Health Interventions

JAMA Network Open
Isabel ChienDanielle Belgrave

Abstract

The mechanisms by which engagement with internet-delivered psychological interventions are associated with depression and anxiety symptoms are unclear. To identify behavior types based on how people engage with an internet-based cognitive behavioral therapy (iCBT) intervention for symptoms of depression and anxiety. Deidentified data on 54 604 adult patients assigned to the Space From Depression and Anxiety treatment program from January 31, 2015, to March 31, 2019, were obtained for probabilistic latent variable modeling using machine learning techniques to infer distinct patient subtypes, based on longitudinal heterogeneity of engagement patterns with iCBT. A clinician-supported iCBT-based program that follows clinical guidelines for treating depression and anxiety, delivered on a web 2.0 platform. Log data from user interactions with the iCBT program to inform engagement patterns over time. Clinical outcomes included symptoms of depression (Patient Health Questionnaire-9 [PHQ-9]) and anxiety (Generalized Anxiety Disorder-7 [GAD-7]); PHQ-9 cut point greater than or equal to 10 and GAD-7 scores greater than or equal to 8 were used to define depression and anxiety. Patients spent a mean (SD) of 111.33 (118.92) minutes on the pl...Continue Reading

References

Sep 15, 2001·Journal of General Internal Medicine·K KroenkeJ B Williams
May 7, 2004·Acta Psychiatrica Scandinavica. Supplementum·J AlonsoUNKNOWN ESEMeD/MHEDEA 2000 Investigators, European Study of the Epidemiology of Mental Disorders (ESEMeD) Project
Oct 4, 2005·Clinical Psychology Review·Andrew C ButlerAaron T Beck
Aug 9, 2011·Journal of Medical Internet Research·Liesje DonkinNick Glozier
Apr 3, 2012·Clinical Psychology Review·Derek Richards, Thomas Richardson
Aug 22, 2013·Journal of Medical Internet Research·Saskia M KeldersJulia Ewc Van Gemert-Pijnen
Feb 4, 2014·Journal of Medical Internet Research·Julia Ewc Van Gemert-PijnenErnst T Bohlmeijer
Jan 7, 2016·Journal of Biomedical Informatics·Nina B BaltierraLisa B Hightow-Weidman
May 4, 2017·IEEE Transactions on Bio-medical Engineering·Ahmed M AlaaMihaela van der Schaar
Jan 15, 2018·Journal of Affective Disorders·Kristina FuhrJan Philipp Klein
Jan 3, 2019·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Gerhard AnderssonPer Carlbring
Mar 23, 2019·The Journal of Clinical Psychiatry·Jesse H WrightMichael E Thase

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Citations

Jul 18, 2020·JAMA Network Open·John TorousHeather L O'Brien
Nov 27, 2020·JMIR Mental Health·Shiri Sadeh-Sharvit, Steven D Hollon
Mar 24, 2021·Journal of Medical Internet Research·Judith J ProchaskaAthena Robinson
Feb 9, 2021·Annual Review of Neuroscience·Claire M Gillan, Robb B Rutledge
Jun 1, 2021·Digital Biomarkers·Priya Kumar, Ieuan Clay

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