PMID: 8590807Dec 1, 1995Paper

A mating type-linked mutation that disrupts the uniparental inheritance of chloroplast DNA also disrupts cell-size control in Chlamydomonas

Molecular Biology of the Cell
E V ArmbrustU W Goodenough

Abstract

An intriguing feature of early zygote development in Chlamydomonas reinhardtii is the active elimination of chloroplast DNA from the mating-type minus parent due presumably to the action of a zygote-specific nuclease. Meiotic progeny thus inherit chloroplast DNA almost exclusively from the mating-type plus parent. The plus-linked nuclear mutation mat3 prevents this selective destruction of minus chloroplast DNA and generates progeny that display a biparental inheritance pattern. Here we show that the mat3 mutation creates additional phenotypes not previously described: the cells are much smaller than wild type and they possess substantially reduced amounts of both mitochondrial and chloroplast DNA. We propose that the primary defect of the mat3 mutation is a disruption of cell-size control and that the inhibition of the uniparental transmission of chloroplast genomes is a secondary consequence of the reduced amount of chloroplast DNA in the mat3 parent.

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Citations

Dec 22, 2010·Sexual Plant Reproduction·Armin Hallmann
Dec 21, 2000·Current Opinion in Microbiology·J Pan, W J Snell
Jul 11, 2001·Genes & Development·J G Umen, U W Goodenough
Oct 3, 2001·Genes & Development·J G Umen, U W Goodenough
May 5, 2001·Annual Review of Plant Physiology and Plant Molecular Biology·Elizabeth H Harris
Oct 17, 2006·PLoS Genetics·Su-Chiung FangJames G Umen
Oct 15, 2014·Proceedings of the National Academy of Sciences of the United States of America·Chia-Hong TsaiChristoph Benning
Jul 24, 2007·Seminars in Cell & Developmental Biology·Ursula GoodenoughJae-Hyeok Lee
Feb 19, 2015·The Plant Journal : for Cell and Molecular Biology·Frederick R Cross, James G Umen
Jun 13, 2006·Biochimica Et Biophysica Acta·Sabeeha S MerchantAimee M Terauchi
Jan 1, 2020·Biotechnology for Biofuels·Tomomi Takeuchi, Christoph Benning
Jan 14, 2020·Current Biology : CB·Frank S HeldtBéla Novák
Jul 21, 2005·Journal of Cell Science·Brian A Bradley, Lynne M Quarmby
Jan 24, 2002·Genetics·Patrick J FerrisUrsula W Goodenough

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